The molecular basis of blood coagulation

PMID: 3286010May 20, 1988Paper

The molecular basis of blood coagulation

Cell

B Furie, B C Furie

Abstract

No abstract listed.

References

Characterization of an almost full-length cDNA coding for human blood coagulation factor X

Jun 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·M R FungR T MacGillivray

Hemophilia B (factor IXSeattle 2) due to a single nucleotide deletion in the gene for factor IX

Oct 1, 1987·The Journal of Clinical Investigation·B G SchachE W Davie

Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene

Jul 14, 1987·Biochemistry·D Z WenJ E Sadler

Occurrence of beta-hydroxylated asparagine residues in non-vitamin K-dependent proteins containing epidermal growth factor-like domains

Nov 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·C T PrzysieckiP A Friedman

Nucleotide sequence of the gene for human prothrombin

Sep 22, 1987·Biochemistry·S J Degen, E W Davie

Cloning of cDNAs coding for the heavy chain region and connecting region of human factor V, a blood coagulation factor with four types of internal repeats

Oct 6, 1987·Biochemistry·W H KaneE W Davie

Organization of the gene for human factor XI

Nov 17, 1987·Biochemistry·R AsakaiD W Chung

Primary structure of bovine vitamin K-dependent protein S

Jun 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·B DahlbäckJ Stenflo

Isolation and sequence of the cDNA for human protein S, a regulator of blood coagulation

Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·A LundwallR Wydro

beta-Hydroxyasparagine in domains homologous to the epidermal growth factor precursor in vitamin K-dependent protein S

Jan 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·J StenfloB Dahlbäck

Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion.

Apr 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J A KantG R Crabtree

Detection and sequence of mutations in the factor VIII gene of haemophiliacs.

May 5, 1985·Nature·J GitschierR M Lawn

Nucleotide sequence of the gene for the gamma chain of human fibrinogen.

Apr 9, 1985·Biochemistry·M W RixonE W Davie

The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs.

Jul 25, 1985·Nucleic Acids Research·R J BeckmannG L Long

The nucleotide sequence of the gene for human protein C.

Jul 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·D C FosterE W Davie

Hemophilia A. Detection of molecular defects and of carriers by DNA analysis.

Oct 3, 1985·The New England Journal of Medicine·S E AntonarakisD N Fass

Nucleotide sequence of the gene for human factor IX (antihemophilic factor B).

Jul 2, 1985·Biochemistry·S YoshitakeK Kurachi

Characterization of the bovine prothrombin gene.

Nov 19, 1985·Biochemistry·D M IrwinR T MacGillivray

An intragenic deletion of the factor IX gene in a family with hemophilia B.

Dec 1, 1985·The Journal of Clinical Investigation·S H ChenK Kurachi

Defective propeptide processing of blood clotting factor IX caused by mutation of arginine to glutamine at position -4.

May 9, 1986·Cell·A K BentleyG G Brownlee

Identification of a missense mutation in the factor VIII gene of a mild hemophiliac.

Jun 13, 1986·Science·J GitschierR M Lawn

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·J J TooleR J Kaufman

Characterization of a thrombomodulin cDNA reveals structural similarity to the low density lipoprotein receptor.

Dec 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·R W JackmanR D Rosenberg

Gene deletions correlate with the development of alloantibodies in von Willebrand disease

May 1, 1987·The Journal of Clinical Investigation·B B Shelton-InloesJ E Sadler

Characterization of five partial deletions of the factor VIII gene

Jun 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·H YoussoufianH H Kazazian

Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA

Aug 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·E K SpicerW H Konigsberg

Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation

Aug 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·P J O'HaraM J Murray

Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin

Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·W H Kane, E W Davie

Recurrent mutations in haemophilia A give evidence for CpG mutation hotspots

Nov 3, 1986·Nature·H YoussoufianS E Antonarakis

Complete cDNA and derived amino acid sequence of human factor V

Jul 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·R J JennyK G Mann

The propeptide of von Willebrand factor independently mediates the assembly of von Willebrand multimers

Jan 29, 1988·Cell·R J WiseS H Orkin

Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII)

Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·D D Pittman, R J Kaufman

Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade

Jul 3, 1987·Cell·J H MorrisseyT S Edgington

Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase

Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·P A PriceG Metz-Virca

Propeptide of human protein C is necessary for gamma-carboxylation

Nov 3, 1987·Biochemistry·D C FosterE W Davie

Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor

Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·D L DiuguidB Furie

Cloning and characterization of human liver cDNA encoding a protein S precursor

Jan 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·J HoskinsG L Long

Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively

May 1, 1987·Somatic Cell and Molecular Genetics·N J RoyleJ L Hamerton

Characterization of a cDNA coding for human factor VII

Apr 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·F S HagenK Kurachi

cDNA sequences for human von Willebrand factor reveal five types of repeated domains and five possible protein sequence polymorphisms

Jun 3, 1986·Biochemistry·B B Shelton-InloesJ E Sadler

Structure of pre-pro-von Willebrand factor and its expression in heterologous cells

Nov 20, 1986·Nature·D T BonthronS H Orkin

Divergent fates of von Willebrand factor and its propolypeptide (von Willebrand antigen II) after secretion from endothelial cells

Apr 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·D D WagnerV J Marder

Molecular cloning of the human gene for von Willebrand factor and identification of the transcription initiation site

Jul 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·C J CollinsD C Lynch

Role of calcium ions and the heavy chain of factor XIa in the activation of human coagulation factor IX

Jun 30, 1987·Biochemistry·D SinhaP N Walsh

Partial factor IX protein in a pedigree with hemophilia B due to a partial gene deletion

Apr 1, 1986·The Journal of Clinical Investigation·G L Bray, A R Thompson

Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition site

Feb 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·J W SuttieG L Long

Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein

May 6, 1986·Biochemistry·K FujikawaE W Davie

Three-dimensional structure of the kringle sequence: structure of prothrombin fragment 1

Jul 15, 1986·Biochemistry·C H Park, A Tulinsky

Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C

Sep 9, 1986·Biochemistry·S P LeytusE W Davie

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Citations

Modelling of factor Xa-inhibitor complexes: a computational flexible docking approach

Feb 18, 1999·Proteins·M S Rao, A J Olson

Low concentrations of fibrinogen increase cell migration speed on fibronectin/fibrinogen composite cables

Jun 8, 2000·Cell Motility and the Cytoskeleton·Z AhmedR A Brown

Linear analogues derived from the first EGF-like domain of human blood coagulation factor VII: enhanced inhibition of FVIIa/TF complex activity by backbone modification through aspartimide formation

Aug 12, 1999·Journal of Peptide Science : an Official Publication of the European Peptide Society·M HusbynP M Fischer

New gene, nel, encoding a M(r) 93 K protein with EGF-like repeats is strongly expressed in neural tissues of early stage chick embryos

Jun 1, 1995·Developmental Dynamics : an Official Publication of the American Association of Anatomists·S MatsuhashiK Hori

Alternative splicing of fibronectin: three variants, three functions.

Oct 1, 1991·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J E Schwarzbauer

The matrix Gla protein gene is a marker of the chondrogenesis cell lineage during mouse development

Feb 1, 1995·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·G LuoG Karsenty

Osteocalcin cluster: implications for functional studies

Mar 1, 1995·Journal of Cellular Biochemistry·C Desbois, G Karsenty

The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha

Jan 1, 1992·Protein Science : a Publication of the Protein Society·M BaronI D Campbell

The astacin family of metalloendopeptidases

Jul 1, 1995·Protein Science : a Publication of the Protein Society·J S Bond, R J Beynon

gamma-Carboxyglutamic acids 36 and 40 do not contribute to human factor IX function

Jan 1, 1997·Protein Science : a Publication of the Protein Society·S GillisM D Bond

Cluster analysis of consensus water sites in thrombin and trypsin shows conservation between serine proteases and contributions to ligand specificity

Oct 29, 1998·Protein Science : a Publication of the Protein Society·P C Sanschagrin, L A Kuhn

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior

Dec 1, 1990·Cancer Metastasis Reviews·J E Testa, J P Quigley

Different evolutionary histories of kringle and protease domains in serine proteases: a typical example of domain evolution

Mar 1, 1995·Journal of Molecular Evolution·K IkeoT Gojobori

Evolution of prothrombin: isolation and characterization of the cDNAs encoding chicken and hagfish prothrombin

Feb 1, 1994·Journal of Molecular Evolution·D K BanfieldR T MacGillivray

Acidic phosphoproteins from bone matrix: a structural rationalization of their role in biomineralization

May 1, 1992·Calcified Tissue International·J P Gorski

Replication of influenza B virus in chicken embryos is suppressed by exogenous aprotinin

Jan 1, 1994·Archives of Virology·O P ZhirnovA V Ovcharenko

Vitamin K-induced changes in markers for osteoblast activity and urinary calcium loss

Aug 1, 1993·Calcified Tissue International·M H KnapenC Vermeer

Progress in the DNA diagnosis of hemophilias

Apr 1, 1991·Annals of Hematology·M Goossens, N Ghanem

Symptomatic hereditary type-II protein C deficiency caused by a missense mutation in exon IX of the protein C gene (Gly381 to Ser)

May 1, 1994·Annals of Hematology·E WittmannH H Watzke

Interaction of apolipoprotein[a] with apolipoproteinB-100 Cys3734 region in lipoprotein[a] is confirmed immunochemically

Jan 1, 1996·Journal of Protein Chemistry·J GuevaraJ T Sparrow

Structural analysis of the uEGF gene in the sea urchin strongylocentrotus purpuratus reveals more similarity to vertebrate than to invertebrate genes with EGF-like repeats

Oct 1, 1989·Journal of Molecular Evolution·M G Delgadillo-ReynosoR A Raff

Elevated urokinase-type plasminogen activator plasma levels are associated with deterioration of liver function but not with hepatocellular carcinoma

Dec 1, 1994·Journal of Gastroenterology·S SatoT Tsuji

Novel cell lines derived from transgenic mice expressing recombinant human proteins. Transgenic hepatoma-derived cell lines

Jan 1, 1992·Cytotechnology·F PerraudA Pavirani

Autoantibodies to coagulation factors and bleeding disorders

Oct 17, 1998·Clinical Reviews in Allergy & Immunology·A E Ahmed

Computational study of coagulation factor VIIa's affinity for phospholipid membranes

Nov 30, 2006·European Biophysics Journal : EBJ·Olivier Taboureau, Ole Hvilsted Olsen

Immune response and immunopathology during toxoplasmosis.

Sep 8, 2012·Seminars in Immunopathology·Christopher D DupontChristopher A Hunter

Cloning of matrix Gla protein in a marine cartilaginous fish, Prionace glauca: preferential protein accumulation in skeletal and vascular systems

Jan 18, 2006·Histochemistry and Cell Biology·J B Ortiz-DelgadoM L Cancela

X-ray crystal structure of CMS1MS2: a high proteolytic activity cysteine proteinase from Carica candamarcensis

May 23, 2012·Amino Acids·Marco T R GomesCarlos E Salas

High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population

Sep 6, 2007·Journal of Human Genetics·Pei-Chieng ChaYusuke Nakamura

The many faces of the contact pathway and their role in thrombosis

Mar 16, 2011·Journal of Thrombosis and Thrombolysis·Rebecca S WoodruffRichard C Becker

Life-threatening bleeding under vitamin K antagonists in spite of an INR in the therapeutic range

Mar 19, 2011·Journal of Thrombosis and Thrombolysis·Mathilde GavilletAnne Angelillo-Scherrer

Accumulation of functional recombinant human coagulation factor IX in transgenic soybean seeds

Nov 12, 2010·Transgenic Research·Nicolau B CunhaElíbio L Rech

Haemodynamic forces on in vitro thrombi: a numerical analysis.

Mar 16, 2012·Medical & Biological Engineering & Computing·Christopher J ButlerGregory J Sheard

A case of factor X (FX) deficiency due to novel mutation V196M, FX Hofu

Feb 14, 2008·International Journal of Hematology·Kenji ShinoharaEriko Morishita

Kringle-dependent structural and functional polymorphism of apolipoprotein (a)

Apr 28, 1995·Biochimica Et Biophysica Acta·A M Scanu, C Edelstein

The relative effects of phylloquinone and menaquinone-4 on the blood coagulation factor synthesis in vitamin K-deficient rats

Aug 3, 1993·Biochemical Pharmacology·M M Groenen-van DoorenC Vermeer

Lipoprotein (a) regulates plasmin generation and inhibition

Jan 1, 1994·Chemistry and Physics of Lipids·J Edelberg, S V Pizzo

Lipid dynamics and peripheral interactions of proteins with membrane surfaces

Sep 6, 1994·Chemistry and Physics of Lipids·P K KinnunenP Mustonen

Increases in pericellular proteolysis at developing neuromuscular junctions in culture

Feb 1, 1992·Developmental Biology·S ChampaneriaM J Anderson

Estrogen induction and contact phase activation of human factor XII

Apr 1, 1996·Steroids·F CitarellaA Fantoni

Isolation and properties of a blood coagulation factor X activator from the venom of king cobra (Ophiophagus hannah)

Oct 1, 1995·Toxicon : Official Journal of the International Society on Toxinology·W H LeeR Gao

The protein C anticoagulant system: inherited defects as basis for venous thrombosis

Jan 1, 1995·Thrombosis Research·B Dahlbäck

Evidence for competition between vitamin K-dependent clotting factors for intracellular processing by the vitamin K-dependent gamma-carboxylase

Oct 1, 1995·Thrombosis Research·C StantonR Wallin

Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor.

Nov 15, 1991·Cell·I RebayS Artavanis-Tsakonas

An unusual mosaic protein with a protease domain, encoded by the nudel gene, is involved in defining embryonic dorsoventral polarity in Drosophila

Sep 8, 1995·Cell·C C Hong, C Hashimoto

States in adherent platelet morphology and the processing of adsorbed protein on biomaterials

Jan 1, 1993·Biomaterials·I A Feuerstein, J I Sheppard

Aprotinin aerosol treatment of influenza and paramyxovirus bronchopneumonia of mice

Feb 1, 1994·Antiviral Research·A V Ovcharenko, O P Zhirnov

Vitamin K-dependent carboxylase: structural requirements for propeptide activation

May 31, 1990·Biochimica Et Biophysica Acta·A CheungM Bernatowicz

Reversible unfolding of an isolated heparin and DNA binding fragment, the first type III module from fibronectin

Feb 13, 1992·Biochimica Et Biophysica Acta·S V LitvinovichK C Ingham

Plasminogen activator inhibitor type-1 interacts exclusively with the proteinase domain of tissue plasminogen activator

Dec 14, 1994·Biochimica Et Biophysica Acta·P BjörquistJ Deinum

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Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

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The molecular basis of blood coagulation

Abstract

References

Why genes in pieces?

Characterization of an almost full-length cDNA coding for human blood coagulation factor X

Hemophilia B (factor IXSeattle 2) due to a single nucleotide deletion in the gene for factor IX

Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene

Occurrence of beta-hydroxylated asparagine residues in non-vitamin K-dependent proteins containing epidermal growth factor-like domains

Nucleotide sequence of the gene for human prothrombin

Cloning of cDNAs coding for the heavy chain region and connecting region of human factor V, a blood coagulation factor with four types of internal repeats

Organization of the gene for human factor XI

Primary structure of bovine vitamin K-dependent protein S

Isolation and sequence of the cDNA for human protein S, a regulator of blood coagulation

beta-Hydroxyasparagine in domains homologous to the epidermal growth factor precursor in vitamin K-dependent protein S

Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion.

Detection and sequence of mutations in the factor VIII gene of haemophiliacs.

Nucleotide sequence of the gene for the gamma chain of human fibrinogen.

The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs.

The nucleotide sequence of the gene for human protein C.

Hemophilia A. Detection of molecular defects and of carriers by DNA analysis.

Nucleotide sequence of the gene for human factor IX (antihemophilic factor B).

Characterization of the bovine prothrombin gene.

An intragenic deletion of the factor IX gene in a family with hemophilia B.

Defective propeptide processing of blood clotting factor IX caused by mutation of arginine to glutamine at position -4.

Identification of a missense mutation in the factor VIII gene of a mild hemophiliac.

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity.

Characterization of a thrombomodulin cDNA reveals structural similarity to the low density lipoprotein receptor.

Gene deletions correlate with the development of alloantibodies in von Willebrand disease

Characterization of five partial deletions of the factor VIII gene

Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA

Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation

Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin

Recurrent mutations in haemophilia A give evidence for CpG mutation hotspots

Complete cDNA and derived amino acid sequence of human factor V

The propeptide of von Willebrand factor independently mediates the assembly of von Willebrand multimers

Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII)

Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade

Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase

Propeptide of human protein C is necessary for gamma-carboxylation

Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor

Cloning and characterization of human liver cDNA encoding a protein S precursor

Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively

Characterization of a cDNA coding for human factor VII

cDNA sequences for human von Willebrand factor reveal five types of repeated domains and five possible protein sequence polymorphisms

Structure of pre-pro-von Willebrand factor and its expression in heterologous cells

Divergent fates of von Willebrand factor and its propolypeptide (von Willebrand antigen II) after secretion from endothelial cells

Molecular cloning of the human gene for von Willebrand factor and identification of the transcription initiation site

Role of calcium ions and the heavy chain of factor XIa in the activation of human coagulation factor IX

Partial factor IX protein in a pedigree with hemophilia B due to a partial gene deletion

Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition site

Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein

Three-dimensional structure of the kringle sequence: structure of prothrombin fragment 1

Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C

Citations

Modelling of factor Xa-inhibitor complexes: a computational flexible docking approach

Low concentrations of fibrinogen increase cell migration speed on fibronectin/fibrinogen composite cables

Linear analogues derived from the first EGF-like domain of human blood coagulation factor VII: enhanced inhibition of FVIIa/TF complex activity by backbone modification through aspartimide formation

New gene, nel, encoding a M(r) 93 K protein with EGF-like repeats is strongly expressed in neural tissues of early stage chick embryos

Alternative splicing of fibronectin: three variants, three functions.

The matrix Gla protein gene is a marker of the chondrogenesis cell lineage during mouse development

Osteocalcin cluster: implications for functional studies

The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha

The astacin family of metalloendopeptidases

gamma-Carboxyglutamic acids 36 and 40 do not contribute to human factor IX function

Cluster analysis of consensus water sites in thrombin and trypsin shows conservation between serine proteases and contributions to ligand specificity

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior

Different evolutionary histories of kringle and protease domains in serine proteases: a typical example of domain evolution

Evolution of prothrombin: isolation and characterization of the cDNAs encoding chicken and hagfish prothrombin

Acidic phosphoproteins from bone matrix: a structural rationalization of their role in biomineralization

Replication of influenza B virus in chicken embryos is suppressed by exogenous aprotinin

Vitamin K-induced changes in markers for osteoblast activity and urinary calcium loss

Progress in the DNA diagnosis of hemophilias

Symptomatic hereditary type-II protein C deficiency caused by a missense mutation in exon IX of the protein C gene (Gly381 to Ser)

Interaction of apolipoprotein[a] with apolipoproteinB-100 Cys3734 region in lipoprotein[a] is confirmed immunochemically

Structural analysis of the uEGF gene in the sea urchin strongylocentrotus purpuratus reveals more similarity to vertebrate than to invertebrate genes with EGF-like repeats

Elevated urokinase-type plasminogen activator plasma levels are associated with deterioration of liver function but not with hepatocellular carcinoma

Novel cell lines derived from transgenic mice expressing recombinant human proteins. Transgenic hepatoma-derived cell lines

Autoantibodies to coagulation factors and bleeding disorders

Computational study of coagulation factor VIIa's affinity for phospholipid membranes

Immune response and immunopathology during toxoplasmosis.