The molecular mechanism of contrast-induced nephropathy (CIN) and its link to in vitro studies on iodinated contrast media (CM)

BioMedicine
Jai-Sing YangFuu-Jen Tsai

Abstract

Iodinated contrast media (iodinated CM) have increased ability to absorb x-rays and to visualize structures that normally are impossible to observe in a radiological examination. The use of iodinated CM may destory renal function, commonly known as contrast-induced nephropathy (CIN), which can result in acute renal failure (ARF). This review article mainly focuses on the following areas: (1) classifications of iodinated CM: ionic or non-ionic, high-osmolarity contrast media (HOCM), low-osmolarity contrast media (LOCM) and iso-osmolarity contrast media (IOCM); (2) an introduction to the physical and chemical properties of the non-ionic iodinated CM; (3) the management of anaphylactic reaction by iodinated CM; (4) a suggested single injection of adult doses and maximum dose for non-ionic iodinated CM; (5) the molecular mechanism of contrast-induced nephropathy (CIN); (6) In vitro studies on iodinated CM. Based on above information, this review article provide an insight for understanding the drug safety of iodinated CM.

References

Mar 1, 1991·Current Problems in Diagnostic Radiology·H O Stolberg, B L McClennan
May 1, 1994·Investigative Radiology·T Almén
Jan 1, 1995·Acta Radiologica. Supplementum·N D PughJ O Karlsson
Aug 29, 2000·BJU International·H S Thomsen, S K Morcos
Feb 27, 2001·Investigative Radiology·V M Runge
Sep 24, 2004·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Nancy Costa
Dec 13, 2005·Journal of Interventional Cardiology·Rainer Schräder
May 26, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Norbert H Lameire
Nov 4, 2006·Expert Review of Cardiovascular Therapy·Peter A McCullough
Apr 7, 2007·The Journal of Allergy and Clinical Immunology·Marianne LerchWerner J Pichler
Apr 21, 2007·Radiology·Richard W Katzberg, Brendan J Barrett
Sep 8, 2007·Der Radiologe·C Erley
Oct 26, 2007·American Journal of Nephrology·Alexey Y KolyadaBertrand L Jaber
Jan 11, 2008·Journal of the American Society of Nephrology : JASN·Yukiyo YokomakuAtsunori Kashiwagi
Jan 22, 2008·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Zuheir KabbaniAntonio Castro
May 17, 2008·Journal of Nuclear Medicine Technology·Jagdish Singh, Aditya Daftary
Mar 18, 2009·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·M C HeinrichM Uder
May 3, 2011·Advances in Chronic Kidney Disease·Steven D Weisbord, Paul M Palevsky
Oct 13, 2011·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Arvind ChopraAnne Menkens
Dec 27, 2011·The American Journal of Medicine·Kimberly L CampbellDavid Axelrod
Mar 13, 2012·World Journal of Gastroenterology : WJG·Xiu-Hua HuPeng Hu
Sep 19, 2012·Advanced Materials·Patrick William GoodwillSteven M Conolly
Apr 4, 2014·Heart Views : the Official Journal of the Gulf Heart Association·Nazar M A MohammedRachel Hajar
Sep 17, 2014·Angiology·Niki KatsikiDimitri P Mikhailidis
Nov 7, 2014·The Journal of Clinical Endocrinology and Metabolism·Sun Y LeeElizabeth N Pearce
Mar 3, 2015·AJR. American Journal of Roentgenology·Matthew S DavenportJames H Ellis
Apr 14, 2015·European Journal of Radiology·Davide PrezziVicky Goh
Oct 16, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Katrina R BeckettJessica M Langer
Nov 18, 2015·Circulation·Julian L WichmannU Joseph Schoepf
Jan 19, 2016·Cardiovascular Drugs and Therapy·George ChalikiasDimitrios N Tziakas
May 14, 2016·The Keio Journal of Medicine·Koichiro Homma
Aug 28, 2016·British Journal of Anaesthesia·G T C WongM G Irwin
Sep 24, 2016·Journal of the American College of Cardiology·Peter A McCulloughAnkit Mehta
May 16, 2017·Advances in Chronic Kidney Disease·Catherine Do
May 26, 2017·World Journal of Nephrology·Sercin Ozkok, Abdullah Ozkok
May 26, 2017·Cardiovascular Diagnosis and Therapy·Ludovico La GruttaMassimo Midiri
Jun 15, 2017·BioMedicine·Jai-Sing YangFuu-Jen Tsai
Jun 24, 2017·Pharmacology & Therapeutics·Charalampos MamoulakisAristides Tsatsakis
Aug 24, 2017·The British Journal of Radiology·Richard HarbronMark S Pearce

❮ Previous
Next ❯

Citations

May 19, 2019·The Journal of Pharmacology and Experimental Therapeutics·Dakota B Ward, Monica A Valentovic
Dec 19, 2020·Revista brasileira de enfermagem·Matheus Santos MoitinhoCassiane Dezoti da Fonseca
Feb 7, 2021·Life Sciences·Ankush Kumar JhaBidya Dhar Sahu
Nov 23, 2021·The Nurse Practitioner·Mohamed Toufic El Hussein, Calla Ha

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA

Software Mentioned

RSROC Contrast Media
RSROC Contrast Media Manual

Related Concepts

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.