The more the better? A meta-analysis on effects of combined cognitive and physical intervention on cognition in healthy older adults

Ageing Research Reviews
Xinyi ZhuJuan Li

Abstract

Both cognitive intervention and physical exercise benefit cognitive function in older adults. It has been suggested that combined cognitive and physical intervention may induce larger effects than cognitive or physical intervention alone, but existing literature has shown mixed results. This meta-analysis aimed at assessing the efficacy of combined intervention on cognition by comparing combined intervention to control group, cognitive intervention and physical exercise. Eligible studies were controlled trials examining the effects of combined intervention on cognition in older adults without known cognitive impairment. Twenty interventional studies comprising 2667 participants were included. Results showed that the overall effect size for combined intervention versus control group was 0.29 (random effects model, p=0.001). Compared to physical exercise, combined intervention produced greater effects on overall effect size (0.22, p<0.01), while no significant difference was found between combined intervention and cognitive intervention. Effects of combined intervention were moderated by age of participants, intervention frequency and setting. The findings suggest that combined intervention demonstrates advantages over control gr...Continue Reading

References

Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Mar 29, 2003·Psychological Science·Stanley Colcombe, Arthur F Kramer
Jun 20, 2003·The New England Journal of Medicine·Joe VergheseHerman Buschke
Aug 3, 2007·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·George W RebokJessica B S Langbaum
Aug 13, 2009·JAMA : the Journal of the American Medical Association·Nikolaos ScarmeasYaakov Stern
Apr 27, 2010·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Verena KlusmannFernando C Dimeo
Dec 4, 2010·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Roee HoltzerJoe Verghese
Dec 7, 2010·Ageing Research Reviews·Huijie LiTing Zhou
Feb 9, 2011·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Stuart W S MacDonaldRoger A Dixon
Mar 17, 2011·The American Journal of Psychiatry·Til WykesPál Czobor
Mar 31, 2011·JAMA : the Journal of the American Medical Association·J Leighton Read, Stephen M Shortell
Nov 8, 2011·Biological Psychiatry·Michael J ValenzuelaUNKNOWN Medical Research Council Cognitive Function and Ageing Study
Dec 14, 2011·Journal of the American Geriatrics Society·Shoshana B Hindin, Elizabeth M Zelinski
Dec 14, 2011·Neurorehabilitation and Neural Repair·Kristopher D Langdon, Dale Corbett
Jan 25, 2012·Archives of Neurology·Susan M LandauWilliam J Jagust
Feb 9, 2012·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Eduard Kraft
Apr 12, 2012·Neurology·Robert S WilsonDavid A Bennett
Jun 8, 2012·Neuropsychological Rehabilitation·Iris-Katharina PennerPasquale Calabrese
Jul 31, 2012·Ageing Research Reviews·Jennifer ReijndersMartin van Boxtel
Mar 23, 2013·Psychonomic Bulletin & Review·Kasey L PowersLouis Alfieri
Apr 16, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Sheung-Tak ChengJohn H M Lam
Sep 17, 2013·Behavioural Brain Research·Andrew M SmithLouis D Matzel
Nov 12, 2013·Psychological Science·Denise C ParkWhitley Aamodt
Dec 19, 2013·Psychological Research·C Shawn GreenTorsten Schubert
Jan 5, 2014·Journal of the American Geriatrics Society·Peter M WayneGloria Y Yeh
Jan 15, 2014·Journal of Aging and Physical Activity·Julia LeónAntonio Oña
Apr 3, 2014·Psychological Research·Hannes NoackFlorian Schmiedek
Apr 8, 2014·Neuroscience and Biobehavioral Reviews·P D BamidisS G Papageorgiou
May 2, 2014·Frontiers in Human Neuroscience·Zuowei WangPriti Shah
Aug 12, 2014·Psychonomic Bulletin & Review·Jacky AuSusanne M Jaeggi

❮ Previous
Next ❯

Citations

Jan 23, 2017·Acta Psychiatrica Scandinavica·N BrondinoP Politi
Sep 5, 2017·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Delphine FagotMichel Audiffren
Nov 2, 2018·Journal of Applied Physiology·Michelle W VossArthur F Kramer
Mar 20, 2019·Australasian Journal on Ageing·Margaret Guthrie
Feb 7, 2019·Geriatrics & Gerontology International·Eva WinzerKarin Schindler
Jan 13, 2018·Nature Reviews. Neuroscience·Mark P MattsonAiwu Cheng
Jun 23, 2020·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Andreas StenlingLiana Machado
Aug 29, 2020·International Journal of Environmental Research and Public Health·Wei GuoBiye Wang
Aug 18, 2020·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Louis BhererArthur F Kramer
Dec 1, 2017·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Meng SunDamien Gallagher
Nov 23, 2017·Frontiers in Aging Neuroscience·Jamie L TaitRobin M Daly
Nov 30, 2019·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Lijuan HuoJuan Li
Jun 9, 2020·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Jianhua HouTong Zhang
Jul 12, 2018·Journal of Alzheimer's Disease : JAD·Bruno BonnechèreBart Jansen
Nov 9, 2018·Frontiers in Aging Neuroscience·Gabriele CattaneoAlvaro Pascual-Leone
Apr 14, 2019·Cognitive, Affective & Behavioral Neuroscience·Debbie M YeeTodd S Braver
Jun 18, 2019·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Mandy RohegerElke Kalbe
May 28, 2019·Journal of Clinical Medicine·Robert Stojan, Claudia Voelcker-Rehage
Jun 7, 2019·Medicine and Science in Sports and Exercise·Fuzhong LiLi-Shan Chou
Dec 21, 2018·Aging Clinical and Experimental Research·Martina MaselliCecilia Laschi
Oct 14, 2020·Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society·Rebecca A GaryDrenna Waldrop
Dec 4, 2020·Journal of Aging and Physical Activity·Valéria Mayaly Alves de OliveiraRodrigo Cappato de Araújo
Dec 6, 2020·Neuroscience and Biobehavioral Reviews·Mónica Muiños, Soledad Ballesteros
Mar 6, 2021·Nursing Forum·Karl Cristie F Figuracion, Frances Marcus Lewis
Mar 9, 2021·Frontiers in Aging Neuroscience·Naina Yuki Vieira JardimCristovam Wanderley Picanço Diniz
Mar 13, 2021·Frontiers in Psychology·Pablo I BurgosMarjorie Woollacott
Mar 28, 2021·Scandinavian Journal of Medicine & Science in Sports·Sarianna SipiläTimo Törmäkangas
Jun 15, 2017·Trends in Neurosciences·David A Raichlen, Gene E Alexander

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.