PMID: 3758071Sep 15, 1986Paper

The mouse myoglobin gene. Characterisation and sequence comparison with other mammalian myoglobin genes

European Journal of Biochemistry
A BlanchetotA J Jeffreys

Abstract

Seal myoglobin (Mb) exons 1 and 3 were used as probes to isolate the functional mouse Mb gene. This gene has a very low level of Mb expression in skeletal muscle. Although it is shorter, the mouse Mb gene displays the common organisation found in human and seal Mb genes. In addition, we have defined blocks of conserved sequences in the 5' flanking region by comparison with other mammalian Mb genes. Moreover, about 10(3) bases upstream of the cap site we identified a repetitive B1 element directly associated with two overlapping open reading frames, containing a putative polyadenylation signal. A polypyrimidine-rich region has also been located upstream from the gene.

References

May 27, 1977·Science·C N ChristianM Nirenberg
Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Apr 11, 1983·Nucleic Acids Research·V F KalbJ B Lingrel
Aug 1, 1984·Molecular and Cellular Biology·K L BennettN D Hastie
Apr 15, 1982·Journal of Molecular Biology·A J JeffreysA C Boyd
Jan 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·M A KeeneS C Elgin
Jul 1, 1983·Analytical Biochemistry·A P Feinberg, B Vogelstein
Mar 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M H FinerP Doty
Jul 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M D BigginG F Hong
Jan 1, 1982·Advances in Comparative Physiology and Biochemistry·P J Butler, D R Jones
Feb 24, 1983·Nature·A BlanchetotA J Jeffreys
Jan 29, 1983·Medicina clínica·M Sabriá Leal
Jan 22, 1982·Nucleic Acids Research·S M Mount

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Citations

Jan 1, 1993·Mammalian Genome : Official Journal of the International Mammalian Genome Society·B Drouet, D Simon-Chazottes
Dec 1, 1992·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·S N VinogradovB Pohajdak
May 28, 2003·Protein Expression and Purification·Marzia BianchiAndrea Brancaccio
Apr 15, 2003·Trends in Cardiovascular Medicine·Daniel J GarryPradeep P A Mammen
Mar 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·W J ParsonsR W Moreadith
Nov 22, 1994·Proceedings of the National Academy of Sciences of the United States of America·G De SanctisM Brunori
Sep 1, 1999·Proceedings of the National Academy of Sciences of the United States of America·A GödeckeJ Schrader
Oct 1, 1991·Journal of Biomolecular Structure & Dynamics·J Tripathi, S K Brahmachari
Dec 1, 1993·Molecular Ecology·R W SladeP T Hale
Aug 3, 2010·The Journal of Experimental Biology·Shane B Kanatous, Pradeep P A Mammen
Apr 1, 1997·Proceedings of the National Academy of Sciences of the United States of America·B D SidellL Costello
Oct 28, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Shannon M HarlanJim Jung-Ching Lin
Nov 9, 2016·Molecular Aspects of Medicine·Paolo AscenziMaria Marino
Mar 31, 2004·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Peter W MaddenRobert E Cashon
Apr 20, 1988·Journal of Molecular Biology·G De SanctisM Brunori

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