PMID: 9420240Jan 7, 1998Paper

The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses

Journal of Virology
J M BergelsonR W Finberg

Abstract

Complementary DNA clones encoding the murine homolog (mCAR) of the human coxsackievirus and adenovirus receptor (CAR) were isolated. Nonpermissive CHO cells transfected with mCAR cDNA became susceptible to infection by coxsackieviruses B3 and B4 and showed increased susceptibility to adenovirus-mediated gene transfer. These results indicate that the same receptor is responsible for virus interactions with both murine and human cells. Analysis of receptor expression in human and murine tissues should be useful in defining factors governing virus tropism in vivo.

References

May 24, 1979·The New England Journal of Medicine·J W YoonA L Notkins
Jul 1, 1989·Journal of Virology·K H Hsu, R L Crowell
Oct 1, 1968·Journal of Virology·L PhilipsonU Pettersson
Jun 1, 1994·Journal of Virology·N LouisJ Chroboczek
Nov 1, 1993·Journal of Virology·J M BergelsonR W Finberg
Apr 1, 1997·Proceedings of the National Academy of Sciences of the United States of America·R P TomkoL Philipson
Apr 1, 1961·Canadian Journal of Microbiology·E I GRODUMS, G DEMPSTER
Dec 1, 1959·Canadian Journal of Microbiology·E I GRODUMS, G DEMPSTER
Dec 1, 1964·Bacteriological Reviews·C M KUNIN

❮ Previous
Next ❯

Citations

Apr 25, 2000·Journal of Virology·K HöflingJ Smith Leser
Aug 11, 2001·Cancer Gene Therapy·P ButtgereitI G Schmidt-Wolf
Mar 29, 2002·Nature Immunology·Malin FlodströmNora Sarvetnick
Dec 26, 2001·The Journal of General Virology·O Brad SpillerB Paul Morgan
Jul 27, 2002·Annual Review of Microbiology·James M Hogle
Sep 12, 2002·Clinical Pharmacokinetics·Cathryn MahTerence R Flotte
Jun 21, 2002·The Journal of General Virology·Heli HarvalaGlyn Stanway
May 27, 2004·Blood·Patricia YotndaMalcolm Brenner
Sep 6, 2005·The Journal of Gene Medicine·Catherine C SmithNigel J Gooderham
Nov 28, 2007·Annual Review of Pathology·Mitra Esfandiarei, Bruce M McManus
May 16, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Matthew J JohnsonRichard A Koup
Jul 19, 2014·Expert Opinion on Drug Delivery·Estrella Lopez-GordoAndrew H Baker
Jun 13, 2015·Experimental Animals·Hye Min ShimHosun Park
Jun 20, 2019·Journal of Biomedical Science·Collins Oduor Owino, Justin Jang Hann Chu
Apr 17, 2020·FEBS Letters·Katherine J D A Excoffon
Oct 28, 1998·Proceedings of the National Academy of Sciences of the United States of America·R P LeonJ DeGregori
Oct 18, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·M R SchmidtR T Woodland
Jul 11, 2000·The European Journal of Neuroscience·D PerreletA C Kato
Jan 21, 2003·Laboratory Investigation; a Journal of Technical Methods and Pathology·Bobby YanagawaBruce M McManus
Mar 22, 2002·Nature Reviews. Cancer·F McCormick
Dec 26, 2001·Journal of Virology·Lane K Law, Beverly L Davidson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.