The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development

FEBS Letters
G SöhlK Willecke

Abstract

A new gap junction gene isolated from rat brain cDNA, mouse retina cDNA and mouse genomic DNA is called connexin36, since it codes for a connexin protein of 321 amino acids corresponding to the theoretical molecular mass of 36045 kDa (rat) and 36084 kDa (mouse). Only one amino acid residue differs between rat and mouse connexin36. In the single murine connexin36 gene, an 1.14-kb intron interrupts the coding region, similar as in the homologous skate connexin35 gene. Because of this unique feature, mouse connexin36 differs from the other 13 murine connexin genes and is suggested to form a new delta subclass of connexins. Connexin36 mRNA (2.9 kb) is highly expressed in adult retina and less abundant in brain where it gradually increased during fetal development until day 7 post partum, and decreased thereafter.

References

Mar 1, 1991·Neuron·M V BennettJ C Sáez
Mar 1, 1990·The Journal of Cell Biology·R L GimlichN B Gilula
Sep 1, 1990·Trends in Biochemical Sciences·B E Kemp, R B Pearson
Dec 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R DermietzelK Willecke
Feb 1, 1989·The Journal of Cell Biology·M Kozak
Dec 1, 1987·The Journal of Cell Biology·E C BeyerD A Goodenough
Jan 30, 1986·Biochimica Et Biophysica Acta·J K Mohana Rao, P Argos
Mar 24, 1994·Nature·V K VerselisT A Bargiello
Aug 1, 1995·Microscopy Research and Technique·J E Cook, D L Becker
Feb 1, 1996·Molecular Biology of the Cell·J O'BrienH Ripps
Jan 1, 1996·Annual Review of Biochemistry·D A GoodenoughD L Paul
Sep 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·R BruzzoneD A Goodenough
Jan 1, 1997·Journal of Neurocytology·P KunzelmannK Willecke
Sep 30, 1998·The European Journal of Neuroscience·D F CondorelliF Cicirata

❮ Previous
Next ❯

Citations

Mar 18, 1999·Developmental Genetics·D FrancisM Delmar
Jun 30, 2000·Cell Biology International·D BeckerP Mobbs
Jun 30, 2000·Cell Biology International·C C Naus, M Bani-Yaghoub
Sep 30, 2004·Anatomy and Embryology·Viviana M BerthoudEric C Beyer
Aug 10, 2006·Cell and Tissue Research·Roberto Bruzzone, Rolf Dermietzel
Mar 26, 2010·Cell and Tissue Research·Melissa MorleyDaniel J Belliveau
Nov 5, 2003·Brain Research Bulletin·Fiona E N LeBeauEberhard H Buhl
Apr 29, 2005·Brain Research. Molecular Brain Research·Xiaosen OuyangJohn O'Brien
Nov 26, 2003·Respiratory Physiology & Neurobiology·Irene C Solomon
May 18, 2000·Brain Research·N BelluardoD F Condorelli
Apr 7, 2000·Brain Research. Brain Research Reviews·M V Bennett
Apr 7, 2000·Brain Research. Brain Research Reviews·D F CondorelliG Mudò
Apr 7, 2000·Brain Research. Brain Research Reviews·D I Vaney, R Weiler
Apr 7, 2000·Brain Research. Brain Research Reviews·T W White, R Bruzzone
Apr 7, 2000·Brain Research. Brain Research Reviews·G SöhlK Willecke
Aug 6, 2000·Brain Research. Brain Research Reviews·R RozentalD C Spray
Apr 7, 2000·Brain Research. Brain Research Reviews·R RozentalM F Mehler
Jan 29, 2000·Brain Research. Developmental Brain Research·G PrimeB Sutor
Feb 9, 2002·Brain Research. Molecular Brain Research·Dimitris PlacantonakisJohn P Welsh
Feb 21, 2003·Gene·Laurent DupaysMagali Théveniau-Ruissy
Dec 23, 1998·Trends in Cell Biology·A M Simon, D A Goodenough
Jul 20, 2002·Respiratory Physiology & Neurobiology·Irene C Solomon, Jay B Dean
Jul 21, 2007·Visual Neuroscience·W Wade KothmannJohn O'Brien
Jun 12, 2010·Visual Neuroscience·Luis Pérez de Sevilla MüllerReto Weiler
Mar 2, 2005·Nature Reviews. Neuroscience·Goran SöhlKlaus Willecke
Oct 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Daniel González-NietoLuis C Barrio
Dec 20, 2008·Proceedings of the National Academy of Sciences of the United States of America·Cantas AlevRolf Dermietzel
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Brady J MaherGary L Westbrook
Aug 16, 2000·Proceedings of the National Academy of Sciences of the United States of America·L VenanceH Monyer
Jun 22, 2000·Proceedings of the National Academy of Sciences of the United States of America·J E RashJ I Nagy
Nov 18, 2010·Integrative and Comparative Biology·Nydia L Rivera-RiveraEduardo Rosa-Molinar
Dec 23, 2008·Epilepsia·Daniela Uziel, Renato Rozental
Jan 15, 2000·Journal of Cardiovascular Electrophysiology·J JalifeD Vaidya

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Brain Research. Brain Research Reviews
Daniele F CondorelliGiuseppa Mudò
© 2022 Meta ULC. All rights reserved