The mutagenic hazards of aquatic sediments: a review

Mutation Research
Guosheng Chen, Paul A White


Sediments are the sink for particle-sorbed contaminants in aquatic systems and can serve as a reservoir of toxic contaminants that continually threaten the health and viability of aquatic biota. This work is a comprehensive review of published studies that investigated the genotoxicity of sediments in rivers, lakes and marine habitats. The Salmonella mutagenicity test is the most frequently used assay and accounts for 41.1% of the available data. The Salmonella data revealed mutagenic potency values for sediment extracts (in revertants per gram dry weight) that spans over seven orders of magnitude from not detectable to highly potent (10(5) rev/g). Analyses of the Salmonella data (n=510) showed significant differences between rural, urban/industrial, and heavily contaminated (e.g., dump) sites assessed using TA98 and TA100 with S9 activation. Additional analyses showed a significant positive correlation between Salmonella mutagenic potency (TA98 and TA100 with S9) and PAH contamination (r2=0.19-0.68). The second and third most commonly used assays for the analysis of sediments and sediment extracts are the SOS Chromotest (9.2%) and the Mutatox assays (7.8%), respectively. These assays are frequently used for rapid initial scree...Continue Reading


Sep 29, 1978·Annals of the New York Academy of Sciences·R A Sonstegard
Feb 11, 1992·Ecotoxicology and Environmental Safety·G T AnkleyG J Niemi
Aug 1, 1992·Mutation Research·V S Houk
Oct 1, 1992·Bulletin of Environmental Contamination and Toxicology·T HashizumeN Kinae
Jan 1, 1992·Bulletin of Environmental Contamination and Toxicology·R K AsthanaR K Singh
Jan 1, 1992·Environmental and Molecular Mutagenesis·D A Pagano, E Zeiger
Dec 1, 1991·Environmental Health Perspectives·M D WatersM A Jackson
Aug 1, 1991·Bulletin of Environmental Contamination and Toxicology·A E Maccubbin, N Ersing
Aug 11, 1991·Ecotoxicology and Environmental Safety·R G Stahl
May 1, 1990·The Science of the Total Environment·C D MetcalfeB P Dunn
May 1, 1990·The Science of the Total Environment·A E MaccubbinB P Dunn
Mar 1, 1990·Archives of Environmental Contamination and Toxicology·M GrifollJ M Bayona
May 1, 1990·The Science of the Total Environment·M A HayesH W Ferguson
Jan 1, 1986·Critical Reviews in Toxicology·H Tokiwa, Y Ohnishi
Jan 1, 1989·Toxicology and Industrial Health·S S Sandhu, W R Lower
Jan 1, 1988·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·D G WaltonH F Stich
Oct 1, 1987·Bulletin of Environmental Contamination and Toxicology·S Oishi, O Takahashi
Jan 1, 1988·Environmental and Molecular Mutagenesis·P L Olive
May 1, 1986·Archives of Environmental Contamination and Toxicology·W R WestM L Lee
Sep 1, 1986·Analytical Chemistry·D Schuetzle, J Lewtas
Nov 1, 1987·Archives of Environmental Contamination and Toxicology·J R MeierL W Condie
Aug 1, 1985·Mutation Research·T SatoT Ishikawa
Jan 1, 1985·Environmental Mutagenesis·R D Snyder, D W Matheson
Jan 1, 1985·Critical Reviews in Food Science and Nutrition·D H Watson
Jun 1, 1985·Mutation Research·P Quillardet, M Hofnung
Aug 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B N AmesF D Lee

❮ Previous
Next ❯


Jun 26, 2013·Archives of Environmental Contamination and Toxicology·Alfredo ParrellaMarina Isidori
Mar 7, 2013·Journal of Molecular Modeling·Elizabeth RinconEduardo Chamorro
Mar 10, 2010·Ecotoxicology·Yukio Yokota, Valeria Matranga
Aug 6, 2010·Environmental Monitoring and Assessment·Juan Fernández-TajesJosefina Méndez
Jul 15, 2011·Environmental Monitoring and Assessment·Reshma Anjum, Abdul Malik
Aug 26, 2009·Environmental Science and Pollution Research International·Markus Hecker, Henner Hollert
Apr 24, 2013·Environmental Science and Pollution Research International·Tilman FloehrHenner Hollert
Sep 10, 2013·Ecotoxicology and Environmental Safety·B Huerta BuitragoS Waara
Nov 28, 2006·Nature Reviews. Cancer·Daniel W Nebert, Timothy P Dalton
Jun 6, 2009·Journal of Toxicology and Environmental Health. Part a·Zhihong CuiJia Cao
Jun 29, 2011·Journal of Toxicology and Environmental Health. Part a·Sandra M PereiraJosefina Méndez
Jun 15, 2011·Photochemistry and Photobiology·Syed Faiz MujtabaRatan Singh Ray
Aug 21, 2007·Applied and Environmental Microbiology·Qingwei LuoLee R Krumholz
Aug 5, 2010·Environmental Health Perspectives·Larry D ClaxtonDavid M DeMarini
May 29, 2014·Ecotoxicology and Environmental Safety·A SarkarSubhodeep Sarker
Nov 15, 2011·Mutation Research·Françoise Vincent-HubertJacek Tronczynski
Sep 7, 2011·Ecotoxicology and Environmental Safety·Thatiana Cappi da CostaVera Maria Ferrão Vargas
Jun 11, 2011·Aquatic Toxicology·C RibeccoO Carnevali
Mar 5, 2011·The Science of the Total Environment·Jianya LingChangkai Zhang
Oct 12, 2010·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Maja ŠrutGöran I V Klobučar
Jan 16, 2010·Ecotoxicology and Environmental Safety·Paula Suares RochaThomas Braunbeck
Nov 17, 2009·Journal of Bioscience and Bioengineering·Piriya KlankeoOnruthai Pinyakong
Nov 7, 2009·The Science of the Total Environment·Laura Vicedo JacociunasHeloísa Helena Rodrigues de Andrade
Nov 6, 2009·Journal of Environmental Management·Rivelino M CavalcanteGeorge S S Freire
Sep 9, 2009·The Science of the Total Environment·Flavio Manoel Rodrigues da Silva JúniorVera Maria Ferrão Vargas
May 30, 2009·Ecotoxicology and Environmental Safety·Paula Suares RochaHenner Hollert
Jan 27, 2009·Mutation Research·Flavio Manoel Rodrigues da Silva Júnior, Vera Maria Ferrão Vargas
Feb 5, 2008·Mutation Research·Nadja SeitzThomas Braunbeck

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.