PMID: 7019687Mar 1, 1981Paper

The mutagenicity of diesel-exhaust particle extracts collected under smog-chamber conditions using the Salmonella typhimurium test system

Mutation Research
L D Claxton, H M Barnes

Abstract

This study was designed to detect the effect that different environmental conditions have upon diesel-exhaust organics. In this study, diesel exhaust was injected into the Calspan smog chamber under different conditions, and the resulting particles were collected upon Pallflex glass-fiber filters. After extraction from the particles with methylene chloride, the organics were solvent exchanged to dimethyl sulfoxide and tested in the Salmonella typhimurium plate-incorporation test. Results demonstrate that the irradiation of propylene, SO2, NO and NO2 produces ozone and a mutagenic moiety. Unless another mitigating factor (e.g., ozone) was present or formed, irradiation did not alter the mutagenic response of the organics. The production or injection of ozone into chamber tended to reduce the mutagenic response of the collected organics. In summary, this study demonstrates that ambient conditions can alter the mutagenic response of diesel-exhaust organics.

References


❮ Previous
Next ❯

Citations

Feb 1, 1983·Mutation Research·E C McCoyR Mermelstein
Jan 1, 1989·Mutation Research·B S Shane, A L Looney
Aug 5, 2010·Environmental Health Perspectives·Larry D ClaxtonDavid M DeMarini
Jun 4, 2004·Environmental Health Perspectives·David M DeMariniPramila Singh
Dec 1, 1986·Environmental Health Perspectives·G MatanoskiL Wallace
Sep 1, 1983·American Journal of Public Health·E T Wei, H P Shu
Mar 1, 1982·Mutation Research·H S Rosenkranz
Aug 1, 1985·Environmental Research·E L WynderH Lahti
Mar 22, 2015·Mutation Research. Reviews in Mutation Research·Larry D Claxton
Jan 1, 1986·Critical Reviews in Toxicology·H Tokiwa, Y Ohnishi
Dec 2, 2004·Mutation Research·Larry D ClaxtonSarah H Warren

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
Ke Li, Shunzhang Yu
Journal of Environmental Health Science & Engineering
Santhanam NeedhidasanRamalingam Chidambaram
Environmental Health Perspectives
Kris Freeman
© 2021 Meta ULC. All rights reserved