The mycobiota of the human body: a spark can start a prairie fire.

Gut Microbes
Di ZhangTingting Wang

Abstract

Mycobiota are inseparable from human health, shaking up the unique position held by bacteria among microorganisms. What is surprising is that this seemingly small species can trigger huge changes in the human body. Dysbiosis and invasion of mycobiota are confirmed to cause disease in different parts of the body. Meanwhile, our body also produces corresponding immune changes upon mycobiota infection. Several recent studies have made a connection between intestinal mycobiota and the human immune system. In this review, we focus on questions related to mycobiota, starting with an introduction of select species, then we summarize the typical diseases caused by mycobiota in different parts of the human body. Moreover, we constructed a framework for the human anti-fungal immune system based on genetics and immunology. Finally, the progression of fungal detection methods is also reviewed.

References

May 1, 1985·Journal of Clinical Microbiology·J W BaileyJ E Bennett
Apr 16, 1993·Science·P O WainrightS K Stickel
Jan 10, 2002·Clinical Microbiology Reviews·H Ruth Ashbee, E Glyn V Evans
Mar 21, 2002·The Lancet Infectious Diseases·Dominique Sanglard, Frank C Odds
Jul 5, 2002·Clinical Microbiology Reviews·Siew Fah Yeo, Brian Wong
Oct 10, 2002·The Journal of Allergy and Clinical Immunology·Harriet A Burge
Nov 6, 2002·The Journal of Allergy and Clinical Immunology·Paul A Greenberger
Mar 21, 2003·European Journal of Immunology·Alessandra CambiCarl G Figdor
Apr 30, 2003·The Journal of Experimental Medicine·Benjamin N GantnerDavid M Underhill
Aug 24, 2004·Infection and Immunity·Mairi C NoverrGary B Huffnagle
Sep 29, 2004·Lancet·Robert A Schwartz
Oct 19, 2004·Clinical Microbiology Reviews·Louis de RepentignyPaul Jolicoeur
Feb 25, 2005·The EMBO Journal·Benjamin N GantnerDavid M Underhill
Apr 13, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Oksana BabulaSteven S Witkin
Aug 5, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Luis Ostrosky-ZeichnerJohn H Rex
Mar 2, 2006·The European Respiratory Journal·D W DenningR M Niven
Mar 7, 2006·Trends in Microbiology·Luigina Romani, Paolo Puccetti
Jul 18, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L Klingspor, S Jalal
Nov 7, 2006·Current Biology : CB·Mauricio Alvarez, Arturo Casadevall
Dec 13, 2006·Nature Immunology·Philip R TaylorGordon D Brown
Dec 22, 2006·Nature·Peter J TurnbaughJeffrey I Gordon
Apr 24, 2007·Nature Immunology·Salomé LeibundGut-LandmannCaetano Reis e Sousa
May 2, 2007·Obstetrics and Gynecology·Paulo C GiraldoSteven S Witkin
Aug 19, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gary W Procop
Sep 28, 2007·The European Respiratory Journal·P LatzinC Casaulta
Apr 9, 2008·Infection and Immunity·Jennifer M DanStuart M Levitz
Jun 28, 2008·Scandinavian Journal of Gastroenterology·Stephan J OttStefan Schreiber
Oct 24, 2008·The New England Journal of Medicine·Pierre-Yves BochudMichael Boeckh
Dec 17, 2008·Mucosal Immunology·S MorettiL Romani
Feb 11, 2009·The Journal of Experimental Medicine·Heather R ContiSarah L Gaffen

❮ Previous
Next ❯

Citations

May 28, 2020·Cancers·Karolina Kaźmierczak-SiedleckaWojciech Makarewicz
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Francesco CaironeStefania Cesa
Aug 28, 2021·Microorganisms·Tereza VyhnalovaPetra Borilova Linhartova

❮ Previous
Next ❯

Methods Mentioned

BETA
bronchoalveolar lavage
PCR
ELISA
electrophoresis

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.