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The Na-K-Cl cotransporter in the brain edema of acute liver failure

Journal of Hepatology

Nov 9, 2010

Arumugam R JayakumarM D Norenberg

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Abstract

Astrocyte swelling and brain edema associated with increased intracranial pressure are major complications of acute liver failure (ALF). The mechanism for such astrocyte swelling/brain edema, however, is not well understood. We recently found that ammonia, a key etiological factor in AL...read more

Mentioned in this Paper

Ischemia
Slc12a2 protein, rat
Necrosis
Acetaminophen
Salicylhydroxamic acid
Tissue Membrane
Bumetanide
Nevus
Talpidae
Calcium
Paper Details
References
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  • Citations23
12345
  • References47
  • Citations23
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The Na-K-Cl cotransporter in the brain edema of acute liver failure

Journal of Hepatology

Nov 9, 2010

Arumugam R JayakumarM D Norenberg

PMID: 21056502

DOI: 10.1016/j.jhep.2010.06.041

Abstract

Astrocyte swelling and brain edema associated with increased intracranial pressure are major complications of acute liver failure (ALF). The mechanism for such astrocyte swelling/brain edema, however, is not well understood. We recently found that ammonia, a key etiological factor in AL...read more

Mentioned in this Paper

Ischemia
Slc12a2 protein, rat
Necrosis
Acetaminophen
Salicylhydroxamic acid
Tissue Membrane
Bumetanide
Nevus
Talpidae
Calcium

Feeds With Similar Papers

Astrocytes and Neurodegeneration

Astrocytes are important for the health and function of the central nervous system. When these cells stop functioning properly, either through gain of function or loss of homeostatic controls, neurodegenerative diseases can occur. Here is the latest research on astrocytes and neurodegeneration.

Related Papers

The Journal of Biological Chemistry

Na-K-Cl Cotransporter-1 in the mechanism of ammonia-induced astrocyte swelling

The Journal of Biological ChemistryOctober 14, 2008
Arumugam R JayakumarM D Norenberg
Metabolic Brain Disease

The Na-K-Cl Co-transporter in astrocyte swelling

Metabolic Brain DiseaseMarch 26, 2010
Arumugam R Jayakumar, M D Norenberg
Paper Details
References
  • References47
  • Citations23
12345
  • References47
  • Citations23
123

Download from

Publisher
PubMed
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