The NADPH oxidase Cpnox1 is required for full pathogenicity of the ergot fungus Claviceps purpurea.

Molecular Plant Pathology
Sabine GiesbertPaul Tudzynski

Abstract

The role of reactive oxygen species (ROS) in interactions between phytopathogenic fungi and their hosts is well established. An oxidative burst mainly caused by superoxide formation by membrane-associated NADPH oxidases is an essential element of plant defence reactions. Apart from primary effects, ROS play a major role as a second messenger in host response. Recently, NADPH oxidase (nox)-encoding genes have been identified in filamentous fungi. Functional analyses have shown that these fungal enzymes are involved in sexual differentiation, and there is growing evidence that they also affect developmental programmes involved in fungus-plant interactions. Here we show that in the biotrophic plant pathogen Claviceps purpurea deletion of the cpnox1 gene, probably encoding an NADPH oxidase, has impact on germination of conidia and pathogenicity: Deltacpnox1 mutants can penetrate the host epidermis, but they are impaired in colonization of the plant ovarian tissue. In the few cases where macroscopic signs of infection (honeydew) appear, they are extremely delayed and fully developed sclerotia have never been observed. C. purpurea Nox1 is important for the interaction with its host, probably by directly affecting pathogenic different...Continue Reading

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Citations

Dec 25, 2012·Antioxidants & Redox Signaling·Margaret E DaubKuang-Ren Chung
May 18, 2012·Molecular Plant-microbe Interactions : MPMI·Nguyen Van ThuatJörg Bormann
Sep 6, 2011·Applied and Environmental Microbiology·Hyo-jin KimMartin B Dickman
May 17, 2011·Annual Review of Phytopathology·Jens Heller, Paul Tudzynski
Mar 23, 2011·Plant Science : an International Journal of Experimental Plant Biology·Carla J EatonBarry Scott
Mar 21, 2009·Fungal Genetics and Biology : FG & B·Wu ZhengZonghua Wang
Nov 6, 2008·Current Opinion in Microbiology·Barry Scott, Carla J Eaton
Jul 11, 2008·Current Opinion in Plant Biology·Martin J Egan, Nicholas J Talbot
Jun 16, 2009·Molecular Plant Pathology·Thomas HaarmannPaul Tudzynski
Nov 27, 2014·Molecular Microbiology·Isabelle LacazeSylvain Brun
Apr 10, 2010·Journal of Integrative Plant Biology·Amrit K NandaChristophe Dunand
Nov 18, 2014·Molecular Microbiology·Ulrike SiegmundPaul Tudzynski
Mar 11, 2015·Environmental Microbiology·Janine HinschPaul Tudzynski
Nov 6, 2012·Current Opinion in Microbiology·Paul TudzynskiUlrike Siegmund
Jan 21, 2012·Biotechnology Advances·Helena HulvováIvo Frébort
Jun 12, 2013·Fungal Genetics and Biology : FG & B·Elizabeth Ripley BallouJ Andrew Alspaugh
Jan 28, 2015·Fungal Genetics and Biology : FG & B·Bang AnShiping Tian
Apr 30, 2017·Molecular Plant Pathology·Sabine KindPaul Tudzynski
Jun 25, 2019·Molecular Plant-microbe Interactions : MPMI·Hua LiGuozheng Qin
Aug 1, 2019·The New Phytologist·Daniela Elisabeth NordziekeAntonio Di Pietro
May 12, 2020·Environmental Microbiology·Xiben WangBarry J Saville
Sep 29, 2017·Fungal biology and biotechnology·Robert MarschallPaul Tudzynski

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