The narrow path to organized LDCT lung cancer screening programs in Europe

Journal of Thoracic Disease
Eugenio Paci

Abstract

A recent position statement by a group of European experts reviewed the current evidence for low-dose computed tomography (LDCT) lung cancer screening, based on the outcomes and screening performance of the published randomized trials and identified actions needed for eventual future implementation. After the National Lung Screening Trial (NLST) outcome publication, guidelines changed in USA and Canada, but there are still problems in real-world screening practice. In Europe any decision was postponed to the publication of the European randomized trial outcomes and recommendations continue to discourage screening for lung cancer in all member countries. The NELSON randomized controlled trial (RCT), the largest one in Europe, outcome results are still waited, whereas the MILD, DANTE, DLSCT and ITALUNG (all with small sample size) RCTs have published mortality and incidence data with adequate follow up. The implementation of an organized screening in Europe is conditioned by a health technology assessment process at European level. According with the European policy, confirmed in the recent European Cancer Code [2015], screening is transferred in current public-health practice according with evidence-based recommendations and bas...Continue Reading

Citations

Jun 12, 2020·Asia-Pacific Journal of Clinical Oncology·Guofeng YangMingqiang Kang
May 22, 2020·Journal of Medical Screening·Eugenio PaciUNKNOWN ITALUNG Working Group

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