The Natural Growth Rate of Residual Juvenile Angiofibroma

Journal of Neurological Surgery. Part B, Skull Base
Nicholas R RowanCarl H Snyderman

Abstract

Objectives  Examine the postoperative growth rate of residual juvenile angiofibroma (JA) in a large series of patients relative to pediatric growth parameters and other prognostic factors. Establish an algorithm for postoperative surveillance of patients with JA. Design  Retrospective case series. Setting  Tertiary referral academic center. Participants  Pediatric patients undergoing surgical resection of JA between September 2005 and June 2015. Main Outcome Measures  Postoperative recurrence and tumor growth rates. Results  Thirty-eight patients were identified with a mean follow-up of 24.1 months. Sixty-eight percent (26/34) of patients achieved gross total resection, and 32% (12/38) had persistent postoperative disease. Of those with postoperative residual tumor, all had preoperative skull base involvement and residual blood supply from the internal carotid artery following embolization. Sixty-seven percent (8/12) of patients with postoperative residual tumor demonstrated radiographic stability of disease with scans being completed approximately every 6 months. Radiographic rates of disease progression ranged from 4.1 to 9.22 mm/year. Conclusions  Patients with preoperative skull base involvement and residual vascularity fol...Continue Reading

Citations

Jul 23, 2019·International Forum of Allergy & Rhinology·Eric W WangCarl H Snyderman
Nov 28, 2020·The Laryngoscope·Alberto SchreiberPiero Nicolai
Dec 7, 2018·Current Opinion in Otolaryngology & Head and Neck Surgery·Giacomo BertazzoniPiero Nicolai
Aug 11, 2021·The Laryngoscope·Maurizio BignamiAndrea Giorgianni

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