The natural history of group B streptococcal colonization in the pregnant woman and her offspring. II. Determination of serum antibody to capsular polysaccharide from type III, group B Streptococcus

American Journal of Obstetrics and Gynecology
C J BakerC W Beachler

Abstract

An investigation of the prevalence and persistence of the concentration of antibody to capsular polysaccharide from type III, group B Streptococcus in sera from 93 pregnant women and their newborn infants is reported. In the majority of women, the concentrations of antibody detected in the sera were low (less than 1 microgram/ml). However, sera from women who were colonized with type III strains of group B streptococci contained significantly higher concentrations of antibody than those from noncolonized women (p = 0.027). No appreciable change in antibody concentration was found in sera collected early in gestation when compared to delivery sera. When maternal-cord serum pairs were analyzed, a significant correlation between concentrations of antibody was found, which indicates that this antibody is transplacentally transferred.

Citations

May 1, 1995·The Australian & New Zealand Journal of Obstetrics & Gynaecology·G L GilbertP McIntyre
Jan 1, 1992·Archives of Disease in Childhood·A GasparoniF Severi
May 1, 1990·American Journal of Reproductive Immunology : AJRI·L R BissetJ F Griffin
Jun 2, 2012·The Pediatric Infectious Disease Journal·Kristen HaywardThomas Koepsell
Nov 9, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Neal J RussellCarol J Baker

Related Concepts

Antibodies, Bacterial
Umbilical Cord Blood
Neonatal Immunity, Maternally-Acquired
Neonatal Disorder
Maternal-Fetal Exchange
Polysaccharides, Bacterial
Streptococcal Infections
Streptococcus agalactiae

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