PMID: 9529638Apr 8, 1998Paper

The natural history of sickle cell disease

Current Opinion in Pediatrics
C HoppeE Vichinsky

Abstract

Sickle cell disease results in significant morbidity and mortality for those affected with this disease. Despite the fact that every case of sickle cell disease results from the same genetic mutation, there is considerable heterogeneity in the clinical course of the disease. Considerable knowledge has been gained regarding the complications of sickle cell disease including pain episodes, infections, stroke, and lung disease. Clarifying the clinical course of sickle cell disease has enabled us to develop therapies to decrease the morbidity of this disease and, with hope, will direct further investigations into novel treatment interventions.

Citations

Jul 12, 2002·Annals of Neurology·Mara PrenglerRobert J Adams
Mar 17, 2007·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Robert B NollAmy Short
Mar 21, 2002·Journal of Pediatric Hematology/oncology·E B FungV A Stallings
Aug 13, 2005·Journal of Pediatric Hematology/oncology·Tonya M PalermoBrian Berman
Feb 15, 2011·Pediatric Blood & Cancer·Sian CottonMeghan E McGrady
May 1, 2001·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·E B FungV A Stallings
Jun 5, 2012·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Michael RothRosanna Ricafort
Jul 22, 2014·European Journal of Haematology·Inês Vaz SilvaAnabela Morais

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

© 2022 Meta ULC. All rights reserved