PMID: 2613383Dec 1, 1989Paper

The natural history of the hypoplastic left heart syndrome

International Journal of Cardiology
Lindsey D AllanM J Tynan

Abstract

In a fetus, examined initially at 22 weeks gestation, we identified the echocardiographic features of a dilated, hypertrophied and poorly contracting left ventricle. The presumptive diagnosis was critical aortic stenosis. Subsequent scans at 32 weeks and at term showed that the left ventricle had not grown since the first study such that the left ventricle had developed the appearance of a hypoplastic and densely echogenic chamber. Thus, in some forms of the hypoplastic left heart syndrome, the left ventricle can be of normal size or even dilated in early pregnancy. This may mean that the more subtle sign of poor left ventricular contraction could be overlooked in a routine four-chamber view obstetric scan.

References

Jun 28, 1986·British Medical Journal·Lindsey D AllanM J Tynan
Mar 26, 1988·British Medical Journal·M WestgrenM Stangenberg
Jun 1, 1987·Journal of Pediatric Surgery·M R HarrisonR W Huff

Citations

Sep 2, 1998·The Annals of Thoracic Surgery·M WeyandH H Scheld
Mar 6, 2004·Seminars in Neonatology : SN·Caren S Goldberg, Carlen A Gomez
Jul 8, 2011·Cardiology in the Young·David R HartgeRoland Axt-Fliedner
Dec 12, 2001·Pediatrics International : Official Journal of the Japan Pediatric Society·G SatomiS Ishikawa
Oct 1, 1995·Journal of Paediatrics and Child Health·D J Penny, R G Weintraub
Mar 1, 1991·Archives of Disease in Childhood·G SharlandLindsey D Allan
May 1, 1991·British Heart Journal·D MaxwellM J Tynan
Jan 1, 1994·British Heart Journal·G SharlandLindsey D Allan
Apr 1, 1994·British Heart Journal·J WyllieS Hunter
May 15, 2007·Orphanet Journal of Rare Diseases·Jean Anne Connor, Ravi Thiagarajan
Jun 17, 2008·Pediatric Research·Robert B HintonD Woodrow Benson
Aug 28, 2014·Cardiology in the Young·F A R JansenMonique C Haak
Aug 1, 2015·Prenatal Diagnosis·Lindsey E HunterJ M Simpson
Jul 11, 2015·Cardiology in the Young·Charles R Cole, Pirooz Eghtesady
Dec 18, 2015·Cardiology in the Young·Michelle Kaplinski, Meryl S Cohen
Nov 7, 2007·Seminars in Thoracic and Cardiovascular Surgery·Michael E MitchellAoy Tomita-Mitchell
May 16, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·D M BardoR P Saneto
Sep 4, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E S Selamet TierneyWayne Tworetzky
May 25, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·V ZidereLindsey D Allan
Mar 21, 2012·Prenatal Diagnosis·E Z ZimmerM Bronshtein
Jan 30, 2007·The Annals of Thoracic Surgery·Pirooz EghtesadyRobert H Beekman
Aug 4, 2001·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·Meryl S Cohen, Jack Rychik
Mar 20, 2012·Early Human Development·Lindsey D Allan
Jan 4, 2012·Journal of the American College of Cardiology·Jeffrey A FeinsteinGerard R Martin
Feb 13, 2001·Seminars in Neonatology : SN·G Sharland
May 29, 2016·Trends in Cardiovascular Medicine·E JaeggiR R Chaturvedi
Jun 4, 2016·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F A R JansenMonique C Haak
Feb 22, 2017·Obstetrics & Gynecology Science·Sun-Young YoonYoung-Hwue Kim
Mar 24, 1998·Prenatal Diagnosis·Ulrich Gembruch
Jul 15, 2000·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J M Simpson
Apr 16, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M Bronshtein, E Z Zimmer
Jul 9, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M C HaakJohn M G van Vugt
Sep 27, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Louise E Wilkins-HaugJames E Lock
May 8, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R Chaoui
Jul 15, 2003·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R Chaoui
Jun 24, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Roland Axt-FliednerUlrich Gembruch
Jun 1, 2003·Journal of Medical Ultrasonics·Katsuhiko TadaShin-Ichi Otsuki
Feb 16, 2005·American Journal of Medical Genetics. Part a·Marja W WesselsPatrick J Willems
Mar 15, 2019·Birth Defects Research·Matthew A Crystal, Lindsay R Freud
Oct 1, 2005·Journal of Clinical Ultrasound : JCU·Theera TongsongChanane Wanapirak
Jul 18, 2018·Echo Research and Practice·Lindsey E Hunter, Anna N Seale
Aug 29, 2014·Cardiology in the Young·Mats Mellander, Helena Gardiner
Dec 26, 2019·Prenatal Diagnosis·Stephanie H GusehLouise E Wilkins-Haug
Sep 27, 2006·Journal of Cardiovascular Medicine·Michele D'AltoRaffaele Calabrò
Feb 18, 2016·Current Opinion in Pediatrics·Lindsay R Freud, Wayne Tworetzky
Jun 21, 2001·Epidemiology·Margaret L. Watkins And, Lorenzo D. Botto
Jan 9, 2019·Nature Genetics·Bill ChaudhryRobert Anderson
May 1, 1996·Pediatric Pathology & Laboratory Medicine : Journal of the Society for Pediatric Pathology, Affiliated with the International Paediatric Pathology Association·R J Scott, I D Sullivan
Mar 15, 2003·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Monique C Haak, John M G van Vugt
Dec 23, 2004·Prenatal Diagnosis·Lindsey D Allan, Ian C Huggon
Jan 28, 2006·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jan Michael SmrcekUlrich Gembruch
Mar 29, 2014·The Journal of Immunology : Official Journal of the American Association of Immunologists·Charles R ColePirooz Eghtesady
Aug 11, 2018·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E Jaeggi, R R Chaturvedi
Jul 27, 2017·Current Cardiology Reports·Matthew Lewis, Marlon Rosenbaum
Mar 3, 2020·Archives of Cardiovascular Diseases·Kevin G Friedman, Wayne Tworetzky
Feb 16, 2021·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Smruti Ranjan MohantySuresh Gururaja Rao

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.