PMID: 6980175May 1, 1982Paper

The nature of Langerhans cells granules: an ultrastructural study

Histopathology
N G El-Labban

Abstract

Langerhans cells and macrophages have been studied in both oral lichen planus lesions and histiocytosis X. Many of the macrophages in both lesions contained phagolysosomes in various stages of degradation. Some of these phagolysosomes were found to develop slender processes and very narrow extensions containing little processed phagocytosed material. These latter structures were indistinguishable from Langerhans granules and were termed Langerhans granule-like structures. There is enough evidence in the present study to suggest that typical Langerhans granules evolve from Langerhans granule-like structures and to confirm that Langerhans cells are a type of macrophage which at one stage of their development show Langerhans granules.

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Citations

Oct 1, 1993·Diagnostic Cytopathology·M AkhtarR Sabbah
Nov 1, 1986·Immunological Investigations·C A PicutR M Lewis
Oct 8, 2005·Expert Review of Proteomics·Chun-Ming HuangCraig A Elmets
Oct 1, 1990·Pathology, Research and Practice·J HirotaY Tatemoto
Jul 4, 2003·The Journal of Investigative Dermatology·Chun-Ming HuangDe-chu C Tang
Sep 18, 2004·Mass Spectrometry Reviews·Chun-Ming HuangDe-Chu C Tang
Apr 27, 2004·Periodontology 2000·Christopher W Cutler, Ravi Jotwani
Jan 1, 1986·Archives of Oral Biology·G M Newcomb, R N Powell
Feb 24, 2010·Toxicology Mechanisms and Methods·Jasmine GeorgeYogeshwer Shukla
Jul 1, 1984·British Journal of Obstetrics and Gynaecology·V Y YuJ Astbury
Aug 1, 1989·The Journal of Dermatology·A de FraissinetteJ Thivolet
Sep 1, 1993·Annals of Saudi Medicine·M AkhtarM Bakry

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