The nature of recollection across months and years and after medial temporal lobe damage

Proceedings of the National Academy of Sciences of the United States of America
Nadine C Heyworth, Larry R Squire

Abstract

We studied the narrative recollections of memory-impaired patients with medial temporal lobe (MTL) damage who took a 25-min guided walk during which 11 planned events occurred. The recollections of the patients, recorded directly after the walk, were compared with the recollections of controls tested directly after the walk (C1), after one month (C2), or after 2.6 years (C3). With respect to memory for the walk, the narrative recollections of the patients were impoverished compared with C1 but resembled the recollections of volunteers tested after long delays (C2 and C3). In addition, how language was used by the patients in their recollections resembled how language was used by groups C2 and C3 (higher-frequency words, less concrete words, fewer nouns, more adverbs, more pronouns, and more indefinite articles). These findings appear to reflect how individuals, either memory-impaired patients or controls, typically speak about the past when memory is weak and lacks detail and need not have special implications about language use and MTL function beyond the domain of memory. A notable exception to the similarity between patient narratives and the narratives of C2 and C3 was that the control groups reported the events of the walk...Continue Reading

References

Jul 1, 1992·Journal of Experimental Psychology. Learning, Memory, and Cognition·F HaistL R Squire
Feb 1, 1981·Cognition·U Neisser
Mar 13, 1998·Annual Review of Psychology·J D Gabrieli
Dec 10, 1999·Memory & Cognition·E T Bergman, H L Roediger
Apr 15, 2003·Neuron·Joseph R MannsLarry R Squire
Feb 24, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yael ShragerLarry R Squire
Dec 17, 2009·Frontiers in Neuroscience·Alex Konkel, Neal J Cohen
Feb 18, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Soyun KimLarry R Squire
Jul 15, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Elizabeth RaceMieke Verfaellie
Jul 4, 2012·Journal of Cognition and Development : Official Journal of the Cognitive Development Society·Elaine ReesePeter A Ornstein
Feb 14, 2013·Proceedings of the National Academy of Sciences of the United States of America·Soyun KimLarry R Squire
Apr 27, 2013·Proceedings of the National Academy of Sciences of the United States of America·Ricardo InsaustiLarry R Squire
Aug 14, 2013·Journal of Experimental Psychology. General·Jake KurczekMelissa Duff
Oct 19, 2013·Learning & Memory·Soyun KimLarry R Squire
Oct 11, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Elizabeth RaceMieke Verfaellie
Apr 1, 2015·Proceedings of the National Academy of Sciences of the United States of America·Soyun KimLarry R Squire
Nov 5, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Caitlin HilvermanMelissa C Duff
Nov 9, 2016·Proceedings of the National Academy of Sciences of the United States of America·Adam J O DedeLarry R Squire
Nov 9, 2016·Proceedings of the National Academy of Sciences of the United States of America·Adam J O DedeLarry R Squire
Dec 3, 2016·Proceedings of the National Academy of Sciences of the United States of America·Zhisen J UrgolitesLarry R Squire
Jul 26, 2017·Proceedings of the National Academy of Sciences of the United States of America·Zhisen J UrgolitesLarry R Squire
Aug 2, 2017·Neuropsychologia·Nazim KevenCarl F Craver
Jun 17, 2018·Learning & Memory·Zhisen J UrgolitesLarry R Squire
Jul 18, 2018·Learning & Memory·Nuttida Rungratsameetaweemana, Larry R Squire

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Citations

Apr 7, 2021·Hippocampus·Caitlin Hilverman, Melissa C Duff

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