PMID: 1214285Dec 4, 1975Paper

The nature of the voltage-dependent conductance of the hemocyanin channel

The Journal of Membrane Biology
R LatorreJ Reyes

Abstract

The electrical responses of individual hemocyanain channels in oxidized cholesterol membranes demonstrate that the voltage-dependent conductance of many-chanel membranes arises from two different mechanisms. These are the voltage-dependent redistribution of channels among several discrete single-channel conductance states themselves. The relaxation time for the discrete conductance changes is of the order of seconds nd the relaxation time of the continuous conductance changes is of the order 10(-4) seconds. As salt concentration in the bathing medium is increased, the single-channel conductance first increases lineary and then saturates. The characteristics of the saturation curves suggest that the continuous conductance changes occur at the edges of the channel and that the mean time an ion spends in the channel is 4 nanoseconds...

References

May 21, 1975·Biochimica Et Biophysica Acta·O AlvarezR Latorre
Jan 1, 1972·Annual Review of Biophysics and Bioengineering·G Ehrenstein, H Lecar
Dec 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·M Montal, P Mueller
Jul 6, 1973·Biochimica Et Biophysica Acta·P Läuger
Dec 31, 1973·The Journal of Membrane Biology·M EisenbergC A Mead
Jan 1, 1970·Progress in Biophysics and Molecular Biology·B Hille
Mar 17, 1972·Biochimica Et Biophysica Acta·L G Gordon, D A Haydon
Jul 1, 1972·The Journal of General Physiology·R LatorreH Lecar
Dec 1, 1971·The Journal of General Physiology·B Hille
Jun 1, 1969·The Journal of General Physiology·R C BeanJ Eichner
Apr 1, 1965·Physiological Reviews·K S COLE

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Citations

Jan 1, 1984·Journal of Mathematical Biology·W F Pickard
Jan 1, 1984·The Journal of Membrane Biology·X CecchiO Alvarez
Jan 1, 1983·The Journal of Membrane Biology·R Latorre, C Miller
Feb 1, 1977·Quarterly Reviews of Biophysics·G Ehrenstein, H Lecar
Oct 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·M B JacksonH Lecar
Jan 1, 1981·The Journal of General Physiology·A L HarrisM V Bennett
Aug 1, 1985·The Journal of Clinical Investigation·D J NelsonR C Bone
May 28, 1979·Biochemical and Biophysical Research Communications·G Menestrina, R Antolini
Dec 8, 1982·Biochimica Et Biophysica Acta·X CecchiO Alvarez
Sep 18, 1980·Biochimica Et Biophysica Acta·T J McIntoshG Zampighi
May 20, 1981·Biochimica Et Biophysica Acta·G Menestrina, R Antolini
Apr 15, 1979·FEBS Letters·R Antolini, G Menestrina
Jan 1, 1987·Archives of Toxicology·R Kroes

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