The nervous system in early HIV infection: a prospective study through 7 years

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
K SamuelssonH E Persson

Abstract

In this study 28 patients with early stage HIV infection (CD4 >280 x 10(6)/l) were subjected to yearly examinations of the nervous system up to 7 years in order to detect any deterioration. Clinical neurological as well as neuropsychological performance was evaluated. The patients also underwent yearly neurophysiological tests (digital EEG, visual evoked potentials, somatosensory evoked potentials, auditory evoked potentials P300 and electroneurography). Every other year, SPECT with (99m)Tc-D,L-hexamethylpropylene amine oxime and brain MRI were performed. Originally, 38 patients were included in the study but only the results of 28 patients who complied with three of more yearly check-ups are presented. The results of yearly investigations of cerebrospinal fluid (CSF) have been presented earlier [Eur J Neurol4 (1997) 1]. All the patients showed signs of HIV in the CSF. Yet, no major deterioration in the neurological, psychological performance, neurophysiological or neuroimaging examinations could be discerned.

References

Dec 1, 1978·Brain : a Journal of Neurology·D S GoodinA Starr
Aug 1, 1992·The American Journal of Psychiatry·R A SternD L Evans
Feb 1, 1991·Archives of General Psychiatry·S LunnL Mathiesen
Jun 1, 1990·Archives of Neurology·I ShimoyamaK Uemura
Jul 1, 1990·Clinical EEG (electroencephalography)·P TinuperT Sacquegna
Sep 30, 1989·BMJ : British Medical Journal·P PortegiesJ Goudsmit
Jan 1, 1988·Neurology·L ResnickW W Tourtellotte
May 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·J P DickC D Marsden
Aug 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·G VillaI Izzi
Feb 1, 1997·Archives of Neurology·D L DamosA M Levine
Sep 5, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·M J HarrisonI Williams
Oct 21, 1999·Scandinavian Journal of Infectious Diseases·B ChristenssonI Rosén
Oct 12, 2000·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J PolichD F Darko
Jan 1, 1997·Journal of Biomedical Science·H.B. Rasmussen

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Citations

Dec 18, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·R Pirskanen-MatellA Ehrnst
Jul 1, 2011·Veterinary Immunology and Immunopathology·Craig MillerSusan VandeWoude
Apr 13, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Karren J TowgoodMichael D Kopelman
Jul 23, 2015·Neural Regeneration Research·Ling-Ling ShenJun Dong
Apr 16, 2016·Journal of Magnetic Resonance Imaging : JMRI·Diogo Goulart CorrêaEmerson Leandro Gasparetto
Oct 17, 2016·Brain Imaging and Behavior·Marloes A M JanssenRoy P C Kessels
Jan 12, 2017·Documenta Ophthalmologica. Advances in Ophthalmology·Jana SzanyiJana Langrova
Dec 17, 2010·AIDS·Judith SchoutenPeter Portegies
May 2, 2014·Nuclear Medicine Communications·Mike SathekgeEkaterina Dadachova
Apr 18, 2019·Documenta Ophthalmologica. Advances in Ophthalmology·Jana SzanyiJana Langrova

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