The neural correlates of desire.

PloS One
Hideaki Kawabata, Semir Zeki

Abstract

In an event-related fMRI study, we scanned eighteen normal human subjects while they viewed three categories of pictures (events, objects and persons) which they classified according to desirability (desirable, indifferent or undesirable). Each category produced activity in a distinct part of the visual brain, thus reflecting its functional specialization. We used conjunction analysis to learn whether there is a brain area which is always active when a desirable picture is viewed, regardless of the category to which it belongs. The conjunction analysis of the contrast desirable > undesirable revealed activity in the superior orbito-frontal cortex. This activity bore a positive linear relationship to the declared level of desirability. The conjunction analysis of desirable > indifferent revealed activity in the mid-cingulate cortex and in the anterior cingulate cortex. In the former, activity was greater for desirable and undesirable stimuli than for stimuli classed as indifferent. Other conjunction analyses produced no significant effects. These results show that categorizing any stimulus according to its desirability activates three different brain areas: the superior orbito-frontal, the mid-cingulate, and the anterior cingula...Continue Reading

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Citations

Mar 20, 2013·Social Cognitive and Affective Neuroscience·Gayannée KediaDavid E J Linden
Apr 12, 2013·Social Cognitive and Affective Neuroscience·Ashley N GearhardtKelly D Brownell
Sep 10, 2014·Neuroscience and Biobehavioral Reviews·Amanda C Hahn, David I Perrett
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Jan 24, 2015·The Journal of Sexual Medicine·Christian KärgelBoris Schiffer
Jul 2, 2011·The Journal of Sexual Medicine·Francesco Bianchi-DemicheliStephanie Ortigue
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Feb 5, 2013·The European Journal of Neuroscience·T Ishizu, S Zeki
May 18, 2020·Social Cognitive and Affective Neuroscience·Janna A DickensonJeffrey S Anderson
Mar 12, 2014··Christopher W. Tyler, Christopher W. Tyler

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