The Neuro Bureau ADHD-200 Preprocessed Repository

BioRxiv : the Preprint Server for Biology
Pierre BellecDaniel S Margulies

Abstract

In 2011, the "ADHD-200 Global Competition" was held with the aim of identifying biomarkers of attention-deficit/hyperactivity disorder from resting-state functional magnetic resonance imaging (rs-fMRI) and structural MRI (s-MRI) data collected on 973 individuals. Statisticians and computer scientists were potentially the most qualified for the machine learning aspect of the competition, but generally lacked the specialized skills to implement the necessary steps of data preparation for rs-fMRI. Realizing this barrier to entry, the Neuro Bureau prospectively collaborated with all competitors by preprocessing the data and sharing these results at the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) (\url{http://www.nitrc.org/frs/?group_id=383}). This "ADHD-200 Preprocessed" release included multiple analytical pipelines to cater to different philosophies of data analysis. The processed derivatives included denoised and registered 4D fMRI volumes, regional time series extracted from brain parcellations, maps of 10 intrinsic connectivity networks, fractional amplitude of low frequency fluctuation, and regional homogeneity, along with grey matter density maps. The data was used by several teams who competed in the ...Continue Reading

Related Concepts

Biological Markers
Fluctuation
Brain Diseases
Derivatives
Magnetic Resonance Imaging
Gray Matter
URL Data Type
Statistician
FMRI
Neuroimaging

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