PMID: 9551491Apr 29, 1998Paper

The neuroanatomy and neurochemistry of schizophrenia

The Psychiatric Clinics of North America
C S Weickert, J E Kleinman

Abstract

Substantial progress, in part owing to recent refinements in methodology, has been made in unraveling the anatomic correlates of schizophrenia. Subtle pathomorphologic changes, distinct from those of well-known degenerative brain disorders, have been observed. Neurochemical characterization has illuminated the nature of these morphologic abnormalities and has pointed to complex dysregulation of neurotransmitters and G proteins. New biochemical hypotheses such as the glutamate hypothesis have replaced and revitalized more established concepts in the neurochemistry of schizophrenia.

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Citations

Jul 5, 2005·Naunyn-Schmiedeberg's Archives of Pharmacology·Suresh SundramBrian Dean
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Dec 20, 2011·Trends in Cognitive Sciences·Michael J Minzenberg, Cameron S Carter

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