The new era in breast cancer. Invasion, size, and nodal involvement dramatically decreasing as a result of mammographic screening

Archives of Surgery
B CadyP T Lavin

Abstract

To describe the magnitude of changes and opportunities that may arise for simplified surgical procedures for women with breast cancer because of the decreasing size and lymph node involvement in invasive breast cancer and earlier presentation of noninvasive and invasive breast cancer. DESIGN AND MAIN OUTCOME ASSESSMENT: Cases (N=1001) of breast cancer from a tertiary and a community hospital between 1989 and 1993 were analyzed for invasion, size, nodal status, and change over time. Ductal carcinoma in situ constituted 14% and 18% of the cancers at the two hospitals. At the tertiary and community hospitals, the mean maximum diameters were 2.1 and 2.0 cm, respectively, and the median maximum diameters were 1.5 and 1.7 cm, respectively, for invasive breast cancer. Twenty-nine percent and 28%, respectively, were 1 cm or less in diameter. Axillary nodal metastases occurred in only 31% of the invasive cancers (tertiary hospital); only 10% had more than three nodal metastases. In the T1a and T1b cases, nodal metastases occurred in only 10% and 43% of the positive nodes were solitary; only 16% had more than three nodal metastases. The proportion of ductal carcinoma in situ, T1a and T1b, and node-negative cases increased significantly o...Continue Reading

Citations

Mar 6, 1999·Breast Cancer Research and Treatment·Y Y Chen, S J Schnitt
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C ReynoldsB J Czerniecki
Mar 11, 2000·Annals of Medicine·P I Haigh, A E Giuliano
Apr 25, 2000·The Australian and New Zealand Journal of Surgery·P Crowe, W Temple
Nov 25, 2000·Breast Cancer : the Journal of the Japanese Breast Cancer Society·P I HaighA E Giuliano
Dec 25, 2000·Breast Cancer : the Journal of the Japanese Breast Cancer Society·H I VargasI Khaikhali
May 12, 2001·The Breast Journal·Blake Cady
Mar 13, 2002·Annals of Surgical Oncology·Stefano ZurridaUmberto Veronesi
Oct 23, 2002·The British Journal of Surgery·M T NanoM Bochner
Apr 26, 2003·The Breast Journal·Hernan I Vargas, Shahla Masood
Jul 3, 2004·ANZ Journal of Surgery·Joon KimAndrew Spillane
Apr 27, 2007·Virchows Archiv : an International Journal of Pathology·Ossama TawfikCarol J Fabian
Aug 1, 2007·Biomarkers in Medicine·Stephen M HewittJoon-Yong Chung
Mar 29, 2011·Annals of Surgical Oncology·Vijayashree Murthy, Ronald S Chamberlain
Feb 2, 2012·International Journal of Breast Cancer·Anastasia Pazaiti, Ian S Fentiman
Oct 12, 2012·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Masakuni NoguchiTakeo Kosaka
Jun 26, 2013·Radiology·Mary C Mahoney, Mary S Newell
Oct 9, 2015·Journal of Experimental & Clinical Cancer Research : CR·Giulia Anna FollacchioVittorio Pasta
Jul 5, 2016·SpringerPlus·Gozde ArslanLevent Celik
Sep 9, 2000·The New England Journal of Medicine·I Funke, W Schraut
Jul 13, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A E GiulianoR R Turner
Jul 13, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·K M McMastersM J Edwards
Nov 26, 1998·Seminars in Surgical Oncology·S Sandrucci, A Mussa
Feb 17, 2001·Breast Cancer : the Journal of the Japanese Breast Cancer Society·M Noguchi M, T Taniya
Jul 20, 2000·The Australian and New Zealand Journal of Surgery·A J Spillane, N P Sacks
Apr 17, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·N F ColJ Lau
May 5, 2004·Annals of Surgical Oncology·Michael S SabelMichael Schultz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.