The new melanoma staging system

Cancer Control : Journal of the Moffitt Cancer Center
Christina J KimAJCC Melanoma Staging Committee

Abstract

Classification schemas for cancers are useful for predicting overall survival and selecting patients for treatment. Historically, the most important factors in determining prognosis in patients with melanoma have been tumor thickness and lymph node status. Sentinel lymph node mapping defines a subset of patients with microscopic metastatic disease can be identified, offering greater accuracy in staging. The authors reviewed studies evaluating the prognostic factors that are significant in predicting survival in patients with melanoma. The newly revised American Joint Committee on Cancer (AJCC) staging system for melanoma is compared with the 1997 AJCC staging system currently in use. The changes in the new AJCC melanoma staging system reflect the new prognostic factors that have been found to be important in predicting survival. These include primary tumor thickness (tumor depth in millimeters is more predictive than the level of invasion) and ulceration, number of metastatic lymph nodes, micrometastatic disease based on the sentinel lymph node biopsy technique or elective node dissection, the site(s) of distant metastatic disease and serum LDH levels. Major revisions have been made to form a new AJCC staging system for melanom...Continue Reading

References

Jul 1, 1982·Histopathology·V J McGovernW H McCarthy
Sep 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A C BuzaidR S Benjamin
Mar 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A C BuzaidR S Benjamin
Nov 4, 1998·JAMA : the Journal of the American Medical Association·S C ShiversD S Reintgen
Mar 10, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J E GershenwaldM I Ross
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M DeichmannH Näher
Apr 12, 2000·The British Journal of Surgery·L JansenB B Kroon
Sep 7, 2000·Journal of the National Cancer Institute·C McNeil
Nov 15, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J ManolaJ Kirkwood
Nov 25, 2000·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·S C ShiversD S Reintgen
Aug 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C M BalchA Morabito
Aug 16, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C M BalchJ F Thompson

❮ Previous
Next ❯

Citations

May 31, 2006·World Journal of Gastroenterology : WJG·Drinko BalicevicBozo Kruslin
May 1, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David F McDermottEvan Hersh
Oct 1, 2009·Journal of Medical Imaging and Radiation Oncology·R KochharP Manoharan
Sep 25, 2012·The American Journal of Dermatopathology·Thilo GambichlerFalk G Bechara
Feb 19, 2014·International Journal of Molecular Medicine·Viola A Heinzelmann-SchwarzJames P Scurry
Dec 7, 2007·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael C CheungLeonidas G Koniaris
Sep 1, 2007·Clinical & Experimental Metastasis·Pia VihinenSeppo O Pyrhönen
Sep 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Daan P LivestroKenneth K Tanabe
Dec 7, 2011·Annals of Surgery·Victoria LyoStanley P L Leong
Dec 8, 2009·Annals of Surgical Oncology·Alfred A MansourHerbert S Schwartz
Feb 14, 2016·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Sara Santos BernardesAlessandra L Cecchini
May 10, 2005·The Journal of Urology·Ricardo Sánchez-OrtizCurtis A Pettaway
Apr 27, 2011·Journal of Cutaneous Pathology·Zhuang FengZhenzhen Zhang
Apr 23, 2008·Pigment Cell & Melanoma Research·Delphine JavelaudAlain Mauviel
Mar 2, 2013·Melanoma Research·Charlotte VaysseMartine Delannes
Jun 15, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ismail MertRouba Ali-Fehmi
Jul 29, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Sara IacoponiUNKNOWN VULCAN Study collaborative group
Jul 17, 2009·The American Journal of Surgical Pathology·Pedram PouryazdanparastPedram Gerami
Dec 28, 2006·Dermatology : International Journal for Clinical and Investigative Dermatology·Georg WeinlichDietmar Fuchs
Oct 11, 2008·The British Journal of Surgery·A B FranckenJ F Thompson
Mar 31, 2005·The American Journal of Dermatopathology·Jiachun X Kung, A Bernard Ackerman
May 15, 2021·Experimental Dermatology·Xosé Luís Deán-Ben, Daniel Razansky
Jan 3, 2012·Journal of Immunological Methods·Douglas M PotterJohn M Kirkwood

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the American Academy of Dermatology
Sue-Min LaiMary Lewis
Expert Review of Anticancer Therapy
Shivani DuggalThomas B Julian
© 2022 Meta ULC. All rights reserved