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The next-generation sequencing revolution and its impact on genomics

Cell

Oct 1, 2013

Daniel C KoboldtElaine R Mardis

Abstract

Genomics is a relatively new scientific discipline, having DNA sequencing as its core technology. As technology has improved the cost and scale of genome characterization over sequencing's 40-year history, the scope of inquiry has commensurately broadened. Massively parallel sequencing ...read more

Mentioned in this Paper

Genome-Wide Association Study
Tumor Cells, Uncertain Whether Benign or Malignant
Pathogenic Aspects
Biochemical Pathway
Adiponectin
Genetic Disorders Screening
Pathogenesis
Exons
ADIPOQ gene
Genome
38
6
6
1555
1
Paper Details
References
  • References93
  • Citations222
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  • References93
  • Citations222
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The next-generation sequencing revolution and its impact on genomics

Cell

Oct 1, 2013

Daniel C KoboldtElaine R Mardis

PMID: 24074859

DOI: 10.1016/j.cell.2013.09.006

Abstract

Genomics is a relatively new scientific discipline, having DNA sequencing as its core technology. As technology has improved the cost and scale of genome characterization over sequencing's 40-year history, the scope of inquiry has commensurately broadened. Massively parallel sequencing ...read more

Mentioned in this Paper

Genome-Wide Association Study
Tumor Cells, Uncertain Whether Benign or Malignant
Pathogenic Aspects
Biochemical Pathway
Adiponectin
Genetic Disorders Screening
Pathogenesis
Exons
ADIPOQ gene
Genome
38
6
6
1555
1

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Cancer Genomics

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research here.

Prenatal Sequencing

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Related Papers

North Carolina Medical Journal

The NCGENES project: exploring the new world of genome sequencing

North Carolina Medical JournalDecember 10, 2013
Ann Katherine M ForemanJames P Evans
Paper Details
References
  • References93
  • Citations222
12345...
  • References93
  • Citations222
12345...

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