The NHLBI Clinical Trials Network in transfusion medicine and hemostasis: an overview

Journal of Clinical Apheresis
Walter H Dzik

Abstract

Transfusion Medicine is a broad discipline that affects the health care of patients from many medical disciplines. Despite the large impact of transfusion therapies on the management of patients with a variety of diseases, there are few clinical trials that evaluate the indications or the effectiveness of transfusion therapies. To respond to this need for better clinical data, the National Heart Lung and Blood Institute of the National Institutes of Health established a clinical trials network in Transfusion Medicine and Hemostasis. Following a competitive selection process, 17 university medical centers and a data coordinating center joined together to collaboratively address clinical questions in transfusion medicine and hemostasis. The activities, organization, and scope of the network is described below. Examples of clinical trials currently in the network "pipeline" are briefly summarized as an overview to more detailed presentations given elsewhere in this symposium.

Citations

Apr 30, 2008·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Holly Barrett Waldron, Charles W Turner
Mar 4, 2009·Clinical Trials : Journal of the Society for Clinical Trials·Jeng-Jong PanCarl F Pieper
Feb 6, 2007·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Araba Afenyi-AnnanNicholas Bandarenko
Jan 15, 2015·Transfusion·Andrew Shih, Donald M Arnold
Oct 19, 2016·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Olivier Garraud
Oct 21, 2006·Current Opinion in Hematology·Lorne Holland, Ravindra Sarode

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.