The nonspecific lymph node uptake of 18F-choline in patients with prostate cancer--a prospective observational study

Nuclear Medicine Review. Central & Eastern Europe
Anja Tea GolubićDražen Huić

Abstract

The aim of this study was to observe and characterize the nonspecific ¹⁸F-choline lymph node uptake in patients with prostate cancer. In this single center, prospective observational study which was done in University Hospital Center Zagreb between December 2012 and October 2014, 69 patients (median age 71 years; range 50-92) with prostate cancer were included. Patients underwent ¹⁸F-choline PET/CT for staging or restaging of prostate cancer. The mean follow-up period was 11.5 months. Kruskal-Wallis test was used to find out if the differences between SUV values of specific and nonspecific accumulation of the tracer are statistically significant. Nonspecific accumulation of ¹⁸F-choline in lymph nodes was found in 36 patients (52.7%). Most of these findings (n = 24) were nonspecific accumulation of the tracer in mediastinal lymph nodes. Other sites of nonspecific tracer uptake were pulmonary hila (n = 20), inguinal lymph nodes (n = 15), and axillary lymph nodes (n = 10). Mean SUV values for mediastinal lymph nodes, pulmonary hila, axillary and inguinal lymph nodes were 4.8, 4.3, 3.1 and 4.1, respectively. Mean SUV value of nonspecific sites of tracer accumulation was lower (not significantly; (p = 0.2) than tracer uptake values ...Continue Reading

Citations

Aug 7, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Michael Soussan
Dec 7, 2018·Nuclear Medicine Communications·Francisco J Gómez-de la FuenteIgnacio Banzo

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