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The NSL complex maintains nuclear architecture stability via lamin A/C acetylation

Nature Cell Biology

Oct 3, 2019

Adam KaroutasA Akhtar

Abstract

While nuclear lamina abnormalities are hallmarks of human diseases, their interplay with epigenetic regulators and precise epigenetic landscape remain poorly understood. Here, we show that loss of the lysine acetyltransferase MOF or its associated NSL-complex members KANSL2 or KANSL3 le...read more

Mentioned in this Paper

Lamins
KANSL3
Patterns
Genome
Nuclear Lamina
Lysine acetyltransferase
Transcription, Genetic
Isotope Labeling, Stable
Cell Nucleus
Chromothripsis
50
3
45
1
Paper Details
References
  • References66
  • Citations1
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  • References66
  • Citations1
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The NSL complex maintains nuclear architecture stability via lamin A/C acetylation

Nature Cell Biology

Oct 3, 2019

Adam KaroutasA Akhtar

PMID: 31576060

DOI: 10.1038/s41556-019-0397-z

Abstract

While nuclear lamina abnormalities are hallmarks of human diseases, their interplay with epigenetic regulators and precise epigenetic landscape remain poorly understood. Here, we show that loss of the lysine acetyltransferase MOF or its associated NSL-complex members KANSL2 or KANSL3 le...read more

Mentioned in this Paper

Lamins
KANSL3
Patterns
Genome
Nuclear Lamina
Lysine acetyltransferase
Transcription, Genetic
Isotope Labeling, Stable
Cell Nucleus
Chromothripsis
50
3
45
1

Similar Papers Found In These Feeds

Nucleolar Dynamics

The nucleolus is the site of ribosome biogenesis, making ribosomal subunits from proteins and ribosomal RNA. Discover the latest research on nucleolar dynamics here.

Parasite Genetics

Parasite genetics is the study of the genetic material of parasites. Here is the latest research on parasite genetics.

Related Papers

Experimental Cell Research

Heterochromatin and histone phosphorylation

Experimental Cell ResearchFebruary 1, 1978
L R GurleyL L Deaven
The Journal of Biological Chemistry

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

The Journal of Biological ChemistryJune 29, 2004
Jesus EspadaManel Esteller
Paper Details
References
  • References66
  • Citations1
12345...
  • References66
  • Citations1
1
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