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The Nucleotide Capture Region of Alpha Hemolysin: Insights into Nanopore Design for DNA Sequencing from Molecular Dynamics Simulations

Nanomaterials

Jan 27, 2015

Richard M A ManaraSyma Khalid

Abstract

Nanopore technology for DNA sequencing is constantly being refined and improved. In strand sequencing a single strand of DNA is fed through a nanopore and subsequent fluctuations in the current are measured. A major hurdle is that the DNA is translocated through the pore at a rate that ...read more

Mentioned in this Paper

Molecular Dynamics
Fluctuation
Human DNA Sequencing
Sequencing
Nuclear Translocation
Pore
Sequence Determinations, DNA
Nucleotides
Exonuclease
Sscp Analysis
3
1
29
Paper Details
References
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The Nucleotide Capture Region of Alpha Hemolysin: Insights into Nanopore Design for DNA Sequencing from Molecular Dynamics Simulations

Nanomaterials

Jan 27, 2015

Richard M A ManaraSyma Khalid

PMID: 28347003

DOI: 10.3390/nano5010144

Abstract

Nanopore technology for DNA sequencing is constantly being refined and improved. In strand sequencing a single strand of DNA is fed through a nanopore and subsequent fluctuations in the current are measured. A major hurdle is that the DNA is translocated through the pore at a rate that ...read more

Mentioned in this Paper

Molecular Dynamics
Fluctuation
Human DNA Sequencing
Sequencing
Nuclear Translocation
Pore
Sequence Determinations, DNA
Nucleotides
Exonuclease
Sscp Analysis
3
1
29

Similar Papers Found In These Feeds

Chromosomal Translocation

Chromosomal Translocation occur when regions on two chromosomes breaks and swaps places or when a region is attached to another chromosome. Discover the latest research on Chromosomal Translocation here.

Related Papers

Nano Letters

Assessing graphene nanopores for sequencing DNA

Nano LettersJuly 12, 2012
David B WellsAleksei Aksimentiev
Journal of the American Chemical Society

Enzyme-modulated DNA translocation through a nanopore

Journal of the American Chemical SocietyDecember 5, 2009
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Paper Details
References
  • References1
  • Citations1
1
  • References1
  • Citations1
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