No abstract listed.
Oxygen uptake in saline-perfused rabbit heart is decreased to a similar extent during reductions in flow and in arterial oxygen concentration
Carbon dioxide exchange across the walls of arterioles: implication for the location of the medullary chemoreceptors
Intravascular membrane oxygenation and carbon dioxide removal with IVOX: can improved design and permissive hypercapnia achieve adequate respiratory support during severe respiratory failure?
Mathematical modeling of chronical hypoxia in tumors considering potential doubling time and hypoxic cell lifetime
Extreme endurance training: evidence of capillary and mitochondria compartmentalization in human skeletal muscle
The skeletal muscle vascular supply closely correlates with the muscle fiber surface area in the rat
Significance of myoglobin as an oxygen store and oxygen transporter in the intermittently perfused human heart: a model study
The Roles of Angiogenesis in Malignant Melanoma: Trends in Basic Science Research over the Last 100 Years
Regional left atrial interstitial remodeling in patients with chronic atrial fibrillation undergoing mitral-valve surgery
Reoxygenation and split-dose response to radiation in a tumour model with Krogh-type vascular geometry
Re-evaluating the use of Voronoi Tessellations in the assessment of oxygen supply from capillaries in muscle
Cellular hyperplasia and hypertrophy, capillary proliferation and myoglobin concentration in the heart of newborn and adult rats at high altitude
The effect of blood flow on oxygen extraction pressures calculated in a model of pointlike erythrocyte sources for rat heart
Calculation of oxygen pressures in tissue with anisotropic capillary orientation. I. Two-dimensional analytical solution for arbitrary capillary characteristics
Enhanced oxygen delivery to primary hepatocytes within a hollow fiber bioreactor facilitated via hemoglobin-based oxygen carriers
Three dimensional microvascular measurements in human endometrium using optical slices from laser scanning confocal microscopy (LSCM)
The realistic prediction of oxygen transport in a tissue-engineered scaffold by introducing time-varying effective diffusion coefficients
The dynamic regulation of microcirculatory conduit function: features relevant to transfusion medicine
An Improved Algorithm and Its Parallel Implementation for Solving a General Blood-Tissue Transport and Metabolism Model
Accelerating the early angiogenesis of tissue engineering constructs in vivo by the use of stem cells cultured in matrigel
A computational model of oxygen delivery by hemoglobin-based oxygen carriers in three-dimensional microvascular networks
Limitations to oxygen transport and utilization during sprint exercise in humans: evidence for a functional reserve in muscle O2 diffusing capacity
Maintenance of heterogeneity of capillary spacing is essential for adequate oxygenation in the soleus muscle of the growing rat
Comparably accelerated vascularization by preincorporation of aortic fragments and mesenchymal stem cells in implanted tissue engineering constructs
Evaluating transcutaneous oximetry data through dynamic modeling. A new method of measuring hypoxic tissue damage
Theoretical analysis of transcapillary fluid exchange: the effects of filtration coefficient and lymph flow on fluid exchange
Capillary configuration and fiber shortening in muscles of the rat hindlimb: correlation between corrosion casts and stereological measurements
The value of mixed venous oxygen saturation as a therapeutic indicator in the treatment of advanced congestive heart failure
A Green's function method for simulation of time-dependent solute transport and reaction in realistic microvascular geometries
A numerical coupling model to analyze the blood flow, temperature, and oxygen transport in human breast tumor under laser irradiation
Microvessel networks [corrected] pre-formed in artificial clinical grade dermal substitutes in vitro using cells from haematopoietic tissues
Blood Flow Versus Hematocrit in Optimization of Oxygen Transfer to Tissue During Fluid Resuscitation
Analytic solution to steady-state radial diffusion of a substrate with first-order reaction kinetics in the tissue of a Krogh's cylinder
Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors
Mathematical model formulation and validation of water and solute transport in whole hamster pancreatic islets
Kinetic modeling in the context of cerebral blood flow quantification by H2(15)O positron emission tomography: the meaning of the permeability coefficient in Renkin-Crone׳s model revisited at capillary scale
Impaired skeletal muscle microvascular function and increased skeletal muscle oxygen consumption in severe falciparum malaria
Heat transfer in a microvascular network: the effect of heart rate on heating and cooling in reptiles (Pogona barbata and Varanus varius)
A computational study of the effect of capillary network anastomoses and tortuosity on oxygen transport
Sarcomere length-induced alterations of capillary hemodynamics in rat spinotrapezius muscle: vasoactive vs passive control
Multiscale Modeling of Antibody-Drug Conjugates: Connecting Tissue and Cellular Distribution to Whole Animal Pharmacokinetics and Potential Implications for Efficacy
Results of the oxygen Fick method in a closed blood circulation model including "total arteriovenous diffusive shunt of oxygen"
Computer simulation of oxygen tension histograms--a possibility for interpretation of microelectrode measurements
Computational Model for Tumor Oxygenation Applied to Clinical Data on Breast Tumor Hemoglobin Concentrations Suggests Vascular Dilatation and Compression
Modeling of Cerebral Oxygen Transport Based on In vivo Microscopic Imaging of Microvascular Network Structure, Blood Flow, and Oxygenation
Evidence for an enduring ischaemic penumbra following central retinal artery occlusion, with implications for fibrinolytic therapy
Evolutionary dynamics of the Warburg effect: glycolysis as a collective action problem among cancer cells
Development of a mathematical model to estimate intra-tumor oxygen concentrations through multi-parametric imaging
Frequency autocorrelation function of stochastically fluctuating fields caused by specific magnetic field inhomogeneities
Oxygen Distributions-Evaluation of Computational Methods, Using a Stochastic Model for Large Tumour Vasculature, to Elucidate the Importance of Considering a Complete Vascular Network
Hypometabolism as the ultimate defence in stress response: how the comparative approach helps understanding of medically relevant questions
Histological Image Processing Features Induce a Quantitative Characterization of Chronic Tumor Hypoxia
Alpha adrenergic receptor blockade increases capillarization and fractional O2 extraction and lowers blood flow in contracting human skeletal muscle
The relative influence of hematocrit and red blood cell velocity on oxygen transport from capillaries to tissue
Increased muscle blood supply and transendothelial nutrient and insulin transport induced by food intake and exercise: effect of obesity and ageing
Functional organization of cerebral microvasculature in a marsupial, the northern quoll (Dasyurus hallucatus)
An examination of the contribution of red cell spacing to the uniformity of oxygen flux at the capillary wall
Television-computer method for in vivo measurement of capillary diameter, based on the passage of red cells
Oxygen transport in resting and contracting hamster cremaster muscles: experimental and theoretical microvascular studies
Impairment of functional capillary density but not oxygen delivery in the hamster window chamber during severe experimental malaria
Effect of RSR13, an allosteric hemoglobin modifier, on oxygenation in murine tumors: an in vivo electron paramagnetic resonance oximetry and bold MRI study
CrossTalk opposing view: De novo capillary recruitment in healthy muscle is not necessary to explain physiological outcomes
Dependence of oxygen delivery on blood flow in rat brain: a 7 tesla nuclear magnetic resonance study
A computational model of oxygen transport in the cerebrocapillary levels for normal and pathologic brain function
Vascular flow reserve as a link between long-term blood pressure level and physical performance capacity in mammals
Enhancement of microvessel tortuosity in the vastus lateralis muscle of old men in response to endurance training
The partial pressure of carbon monoxide in human tissues calculated using a parallel capillary-tissue cylinder model
Effect of sepsis on skeletal muscle oxygen consumption and tissue oxygenation: interpreting capillary oxygen transport data using a mathematical model
Time-dependant oxygen partial pressure in capillaries and tissue in the hamster window chamber model
Lognormal distribution of intercapillary distance in normal and hypertrophic rat heart as estimated by the method of concentric circles: its effect on tissue oxygenation
Oxygen diffusivity in tumor tissue (DS-carcinosarcoma) under temperature conditions within the range of 20--40 degrees C
Simulation of oxygen carrier mediated oxygen transport to C3A hepatoma cells housed within a hollow fiber bioreactor
Tissue-blood exchange of extravascular longitudinal magnetization with account of intracompartmental diffusion
Effect of repetitive ischemia on myocardial oxygen tension in isolated perfused and hypoperfused rat hearts
Predicted permeability parameters of human ovarian tissue cells to various cryoprotectants and water
Effect of membranes on oxygen transfer rate and consumption within a newly developed three-compartment bioartificial liver device: Advanced experimental and theoretical studies
Microcirculation of left atrial muscle, cerebral cortex and mesentery of the cat. A comparative analysis
Role of endothelium-derived nitric oxide in the regulation of cardiac oxygen metabolism: implications in health and disease
OBSERVATIONS ON THE ROLE OF DIMINISHED OXYGEN TENSION IN THE FUNCTIONAL HYPEREMIA OF SKELETAL MUSCLE
Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis
Longitudinal gradients in periarteriolar oxygen tension. A possible mechanism for the participation of oxygen in local regulation of blood flow
Effect of carotid artery ligation and infusion of fluosol FC-43 emulsion on brain surface oxygen tensions
Heterogeneity of red blood cell perfusion in capillary networks supplied by a single arteriole in resting skeletal muscle
Role of resistance and exchange vessels in local microvascular control of skeletal muscle oxygenation in the dog
Capillary limitation of oxygen distribution in the isolated rete mirabile of the eel (Anguilla anguilla)
Instantaneous femoral artery pressure-flow relations in supine anesthetized dogs and the effect of unilateral elevation of femoral venous pressure
Augmented tissue oxygen supply during striated muscle contraction in the hamster. Relative contributions of capillary recruitment, functional dilation, and reduced tissue PO2
Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: the role of abnormal peripheral oxygen extraction
The significance of the NH3-NH+(4) equilibrium on the passage of 13N-ammonia from blood to brain. A new regional residue detection model
Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood-brain barrier
Clinical approach to wounds: débridement and wound bed preparation including the use of dressings and wound-healing adjuvants
Targeted oxygen delivery within hepatic hollow fiber bioreactors via supplementation of hemoglobin-based oxygen carriers
A compartmental capillary, convolution integration model to investigate nutrient transport and metabolism in vivo from paired indicator/nutrient dilution curves
On the effect of calcium antagonists on cerebral blood flow in rats. A comparison of nimodipine and flunarizine
In Silico Model of Critical Cerebral Oxygenation after Traumatic Brain Injury: Implications for Rescuing Hypoxic Tissue
Oxygen partial pressure in outer layers of skin: simulation using three-dimensional multilayered models
Some factors of significance for respiratory gas exchange in muscle tissue. A mathematical analysis of a capillary model
The time dependence of training-induced increase in skeletal muscle capillarization and the spatial capillary to fibre relationship in normal and neovascularized skeletal muscle of rats
Adaptive changes in work capacity, skeletal muscle capillarization and enzyme levels during training and detraining
Human microvascular imaging: a review of skin and tongue videomicroscopy techniques and analysing variables
Skeletal muscle intrinsic functional properties are preserved in a model of erythropoietin deficient mice exposed to hypoxia
Mechanistic modelling of dynamic MRI data predicts that tumour heterogeneity decreases therapeutic response
Effect of decreased O2 supply on skeletal muscle oxygenation and O2 consumption during sepsis: role of heterogeneous capillary spacing and blood flow
Porous medium 3D flow simulation of contrast media washout in cardiac MRI reflects myocardial injury
Estimation of oxygen distribution in RIF-1 tumors by diffusion model-based interpretation of pimonidazole hypoxia and eppendorf measurements
Local frequency density of states around field inhomogeneities in magnetic resonance imaging: effects of diffusion
Peripheral oxygen transport and utilization in rats following continued selective breeding for endurance running capacity
Anoxic cell core can promote necrotic cell death in cardiomyocytes at physiological extracellular PO2
Edward F. Adolph Distinguished Lecture. Contemporary model of muscle microcirculation: gateway to function and dysfunction
Mechanistic modelling of cancer: some reflections from software engineering and philosophy of science
Microvascular hemodynamics in human hypothermic circulatory arrest and selective antegrade cerebral perfusion
Simulation study of pO2 distribution in induced tumour masses and normal tissues within a microcirculation environment
Role of erythrocyte-released ATP in the regulation of microvascular oxygen supply in skeletal muscle
Estimating oxygen consumption rates of arteriolar walls under physiological conditions in rat skeletal muscle
Numerical modeling of oxygen distributions in cortical and cancellous bone: oxygen availability governs osteonal and trabecular dimensions
Targeting tumor interstitial fluid pressure: will it yield novel successful therapies for solid tumors?
Race-specific differences in the phase coherence between blood flow and oxygenation: A simultaneous NIRS, white light spectroscopy and LDF study.
Krogh's capillary recruitment hypothesis, 100 years on: Is the opening of previously closed capillaries necessary to ensure muscle oxygenation during exercise?
Impaired skeletal muscle performance as a consequence of random functional capillary rarefaction can be restored with overload-dependent angiogenesis
Spectrophotometric measurements of haemoglobin saturation and concentration in skin during the tuberculin reaction in normal human subjects
Relation of Retinal Oxygen Measures to Electrophysiology and Survival Indicators after Permanent, Incomplete Ischemia in Rats.
Three-Dimensional Characterization of the Normal Human Parafoveal Microvasculature Using Structural Criteria and High-Resolution Confocal Microscopy
The O2-exchange between capillaries and tissues. I. O2-concentration profile in blood capillaries and their environment
The Erlanger Microlightguide Photometer: a new concept for monitoring intracapillary oxygen supply of tissue--first results and a review of the physiological basis
Capillary recruitment in response to tissue hypoxia and its dependence on red blood cell deformability
Microvascular and interstitial PO(2) measurements in rat skeletal muscle by phosphorescence quenching
In vitro kinetic studies on the mechanism of oxygen-dependent cellular uptake of copper radiopharmaceuticals
Measurement of renal tissue oxygenation with blood oxygen level-dependent MRI and oxygen transit modeling
The blood oxygen transport system. A numerical simulation of capillary-tissue respiratory gas exchange
Diffusion error and specific consumption of the Pt electrode during pO2 measurements in the steady state
Effect of restricted water exchange on cerebral blood flow values calculated with arterial spin tagging: a theoretical investigation
A mathematical model of O2 transport in the rat outer medulla. I. Model formulation and baseline results
A new method for measuring the oxygen diffusion constant and oxygen consumption rate of arteriolar walls
Regulation of human skeletal muscle perfusion and its heterogeneity during exercise in moderate hypoxia
Lack of functional effects of neuromuscular electrical stimulation on skeletal muscle oxidative metabolism in healthy humans
Capillary recruitment in a theoretical model for blood flow regulation in heterogeneous microvessel networks
Multilevel functional genomics data integration as a tool for understanding physiology: a network biology perspective
Automated assessment of absolute nailfold capillary number on videocapillaroscopic images: Proof of principle and validation in systemic sclerosis
Morphometry of the normal retinal periarteral capillary-free zone and changes during severe nonproliferative diabetic retinopathy
High altitude tissue adaptation in Andean coots: capillarity, fibre area, fibre type and enzymatic activities of skeletal muscle
Tumor vascular area correlates with photosensitizer uptake: analysis of verteporfin microvascular delivery in the Dunning rat prostate tumor
Low-intensity training increases peak arm VO2 by enhancing both convective and diffusive O2 delivery
One hundred years of pulmonary function testing: a perspective on 'The diffusion of gases through the lungs of man' by Marie Krogh
Defining Physiological Normoxia for Improved Translation of Cell Physiology to Animal Models and Humans
Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates.
Measurement of gas pressure of human extremity musculature and its relation to circulation; method and results
Two-photon microscopy measurement of cerebral metabolic rate of oxygen using periarteriolar oxygen concentration gradients
Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic Dunning prostate tumors
Anatomic capillarization is maintained in relative excess of fiber oxidative capacity in some skeletal muscles of late middle-aged rats
August Krogh's theory of muscle microvascular control and oxygen delivery: a paradigm shift based on new data.
Blood flow, capillary transit times, and tissue oxygenation: the centennial of capillary recruitment
A two-compartment model of oxygen transport in skeletal muscle using continuously distributed capillaries.
Teleost red blood cells actively enhance the passive diffusion of oxygen that was discovered by August Krogh.
How cardiac output is regulated: August Krogh's proto-Guytonian understanding of the importance of venous return.
Sex Differences In Cardiorespiratory Fitness Are Explained By Blood Volume And Oxygen Carrying Capacity.
Continuous monitoring of interstitial tissue oxygen using subcutaneous oxygen microsensors: In vivo characterization in healthy volunteers
Brain microvasculature has a common topology with local differences in geometry that match metabolic load.
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