PMID: 8601116Feb 17, 1996Paper

The number needed to treat: a clinically useful nomogram in its proper context

BMJ : British Medical Journal
G ChatellierP Degoulet

Abstract

The number needed to treat is a meaningful way of expressing the benefit of an active treatment over a control. It can be used either for summarising the results of a therapeutic trial or for medical decision making about an individual patient, but its use at the bedside has been impeded by the need for time consuming calculations. A nomogram has therefore been devised that will greatly simplify the calculations. Since calculations are now easy, the number needed to treat can be used to access the value of several interventions, although it does have its limitations. In particular it should not be used when it is not known whether the relative risk reduction associated with an intervention is constant for all levels of risk, or for periods of time longer than that studied in the original trials.

Citations

Apr 14, 2005·World Journal of Surgery·Martin R Tramèr, Bernhard Walder
Dec 2, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·A K ThompsonE O Meltzer
Sep 2, 2000·Journal of Evaluation in Clinical Practice·M L Green
Feb 24, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·C SchraederM Sager
Jan 6, 2005·The Journal of Cardiovascular Nursing·Salvador Pita-FernándezSonia Pértega-Díaz
Oct 23, 1997·British Journal of Obstetrics and Gynaecology·K S Khan, P F Chien
Jul 1, 1997·British Journal of Obstetrics and Gynaecology·L NordströmH Rydhstroem
May 11, 1996·BMJ : British Medical Journal·J Thomas, C Sharp
Jun 1, 1996·BMJ : British Medical Journal·R Gray, J Northover
Aug 24, 1996·BMJ : British Medical Journal·A Tonks, R Smith
Nov 3, 2011·BMC Infectious Diseases·Michael K MwanikiJames A Berkley
Aug 18, 2004·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Alexandra BarrattUNKNOWN Evidence-Based Medicine Teaching Tips Working Group
Oct 31, 2002·American Journal of Public Health·Gabriel M LeungAnthony J Hedley
Oct 19, 2010·Indian Journal of Ophthalmology·Rajeev Kumar Malhotra, A Indrayan
Mar 7, 2006·PLoS Medicine·Chit Ming WongJoseph S M Peiris
Jun 28, 2014·Advances in Chronic Kidney Disease·Jerry Yee
Jan 18, 2006·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Miguel Bussière, Samuel Wiebe
Jun 1, 2000·Journal of the American Medical Informatics Association : JAMIA·H P Lehmann, S N Goodman
Apr 18, 2001·Controlled Clinical Trials·R Bender
Mar 16, 2012·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·F EckertA-C Müller
Aug 7, 2008·Reproductive Biomedicine Online·Peter PlatteauPaul Devroey
Aug 10, 2015·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Stephan C BischoffAndré van Gossum
Oct 22, 2013·Alimentary Pharmacology & Therapeutics·V S AkshintalaV K Singh
Aug 17, 2006·Internal Medicine Journal·I ScottD Campbell
Oct 13, 2011·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Richard A BryantThananet Chantaluckwong
Apr 6, 2004·The American Journal of Medicine·David A AlterAndreas Laupacis
Oct 7, 2004·Archives of Physical Medicine and Rehabilitation·Douglas L Weeks, J Timothy Noteboom
Jun 27, 1998·Lancet·F R ArtalejoP Guallar-Castillón
Aug 22, 2015·Journal of Clinical Anesthesia·Thomas DanningerStavros G Memtsoudis
Feb 11, 2014·Journal of Hepatology·Hamish InnesSharon J Hutchinson
Apr 24, 2010·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Jeff J GuoDennis W Raisch
Jul 1, 2010·Journal of the Saudi Heart Association·Mahmoud Elbarbary

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