The number of neurons in dorsal root ganglia L4-L6 of the rat

The Anatomical Record
H Schmalbruch

Abstract

The number of neurons in the dorsal root ganglia L4-L6 of the rat was determined because published data are inconsistent and in general incompatible with the number of afferent axons in the sciatic nerve. Nucleoli were counted in serial sections; epoxy-resin sections 3 microns thick, or paraffin sections 5 microns thick, or unstained 12-microns paraffin sections of osmicated tissue were used. Correction factors for split and multiple nucleoli were obtained by counting nucleolar profiles in consecutive sections of identified cells. Dividing the number of nucleolar profiles into the number of cells gave the factor by which the counts of nucleolar profiles had to be multiplied to obtain the number of neurons. The ganglia L4, L5, and L6 contained about 12,000, 15,000 and 14,000 neurons, respectively, when resin sections were used. The standard deviation for the average of 41,000 neurons in the three ganglia was 8% of the mean value. The results compare well with the number of dorsal root fibers, and with the fact that the sciatic nerve at midthigh, to which less than half of the neurons connect, contains 19,000 afferent axons. The data obtained from the paraffin series were 23% smaller, but still considerably higher and less variab...Continue Reading

References

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Citations

Nov 27, 1995·Brain Research·H Schmalbruch, A Rosenthal
Dec 1, 1990·Journal of Neuroscience Methods·R E CoggeshallC M Klein
Jan 1, 1992·Trends in Neurosciences·R E Coggeshall
Sep 12, 2001·Trends in Neurosciences·C S von Bartheld
May 10, 2001·Neuroscience Letters·H A Mohammed, R M Santer
Dec 17, 2008·Neurological Research·Andrew M HartMikael Wiberg
Apr 17, 2012·Somatosensory & Motor Research·J C SoaresS M M Matheus
Jan 1, 1993·Somatosensory & Motor Research·T CecchiniP Del Grande
Jan 1, 1991·Somatosensory & Motor Research·M Devor, R Govrin-Lippmann
Jan 1, 1991·Somatosensory & Motor Research·R A La ForteR E Coggeshall
Jan 1, 1995·Somatosensory & Motor Research·J E SwettP G Miller
Jan 26, 2005·The Journal of Comparative Neurology·Lu-Ting KuoMichael J Groves
Oct 1, 1994·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·B CalzadaJ A Vega
Mar 2, 2016·Proceedings of the National Academy of Sciences of the United States of America·Jami L SalomanBrian M Davis
Aug 25, 2004·Journal of Neuroscience Methods·Pierre LozeronHenning Schmalbruch
Sep 8, 1988·The Journal of Comparative Neurology·L M Pubols, M E Foglesong
Jun 17, 2008·The Journal of Physiology·Véronique DouardRonaldo P Ferraris
Feb 4, 2014·Journal of Neuroscience Methods·Luis E SavastanoSean I Patterson
May 27, 2016·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Katarina VukojevicMirna Saraga-Babic
May 16, 2006·Toxicologic Pathology·Brad BolonUNKNOWN Ad Hoc Working Group of the STP Scientific and Regulatory Policy Committee
Apr 27, 2017·Plastic and Reconstructive Surgery·Joseph CatapanoGregory H Borschel
Aug 10, 1999·The Journal of Comparative Neurology·J DegnJ Jakobsen
Jul 13, 2002·The Journal of Comparative Neurology·Paul B Farel
Nov 1, 1987·The Anatomical Record·H Schmalbruch

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