PMID: 20646610Jul 22, 2010Paper

The observation of the influence about blood pressure and cardiovascular B ultrasonic wave by chronic intermittent hypoxia

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Ying WangMing-xian Li

Abstract

To investigate the influence of left heart function in obstructive sleep apnea by CIH, and explore left heart function and blood pressures before or after CPAP. 75 OSA were divided into two groups: 40 patients blood pressures were coincident with diagnostic standard of hypertension recording; 35 patients blood pressures were non-hypertension recording. The control group included 30. healthy adults. The blood pressures before and also after sleep, left ventricular ejection fraction (LVEF), shortening fraction (FS), E, A and E/A were compared with those of normal control subjects. Analyzed BP, LVEF and E/A after CPAP. (1) The blood pressure soon after getting up in the morning (150.80+/-20.73/108.0+/-15.34) mm Hg (1 mm Hg=0.133 kPa) was significantly higher than that before sleep (134.16+/-18.33/90.09+/-11.24) mm Hg (P<0.001). (2) Multiple parameters including LVEF, FS and E/A, were impaired in OSA patients relative to the control subjects (P<0.05 or P<0.01), OSA affected cardiovascular function directly; E/A was significantly decreased in obstructive sleep apnea unallied hypertension than that in normal control subjects; E/A was conspicuously decreased in obstructive sleep apnea associated hypertension comparing with that in obs...Continue Reading

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