PMID: 6169012Aug 11, 1981Paper

The occurrence of families of repetitive sequences in a library of cloned cDNA from human lymphocytes

Nucleic Acids Research
J M CramptonT F Knapp

Abstract

A library of cloned cDNAs representative of lymphocyte total poly(A)+ RNA was screened with total DNA probes at high clone density. 10% of the recombinants showed the presence of sequences which are repeated in the genome. Further analysis of six such isolated cDNA clones indicated that they contain different families of repetitive sequences with reiteration frequencies of between 150 and 45,000 copies per haploid genomes. Five of the six clones were found to contain single copy sequences as well as a repetitive sequence. cDNA clones containing repetitive sequences have been found to be derived from high, intermediate and low abundance classes of lymphocyte poly(A)+ RNA.

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Citations

Mar 1, 1991·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·U Hochgeschwender, M B Brennan
Oct 1, 1986·Human Genetics·K PaulsenK Davies
Jan 1, 1983·Molecular & General Genetics : MGG·F S NallasethM J Dewey
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May 1, 1985·Developmental Biology·G KaplanR Bachvarova
Oct 1, 1994·Trends in Genetics : TIG·M Lovett
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Sep 25, 1985·Nucleic Acids Research·R FultonJ T Knowler
Aug 5, 1998·Proceedings of the National Academy of Sciences of the United States of America·W Makalowski, M S Boguski
Aug 1, 1995·Mammalian Genome : Official Journal of the International Mammalian Genome Society·R A Van den BusscheR J Baker
May 1, 1997·Nucleic Acids Research·R FislageH Oberender
Jun 24, 1982·Nature·E H Davidson, J W Posakony
Jun 1, 1996·Molecular Biotechnology·R S Devon, A J Brookes

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