PMID: 2890729Jul 1, 1987Paper

The occurrence of multiple endocrine neoplasia type IIb, in two children of an affected mother

Journal of Oral Pathology
J J SciubbaJ N Attie

Abstract

Two children with multiple endocrine neoplasia syndrome, Type IIb, (MEN IIb), whose natural mother died from complications of general anesthesia, due to undiagnosed bilateral pheochromocytomas, are described. Of particular interest is the fact that the daughter presented with many stigmata of the syndrome, including the typical facies, while her brother had no obvious clinical manifestations of the syndrome. Both children to date have undergone total thyroidectomy, and pathology reports have confirmed the presence of medullary thyroid carcinoma.

References

Feb 1, 1979·The Surgical Clinics of North America·J A NortonS A Wells
Jun 1, 1976·Oral Surgery, Oral Medicine, and Oral Pathology·J A CarneyS A Lovestedt
Jan 1, 1973·The Journal of Clinical Endocrinology and Metabolism·J F HennessyD A Ontjes
Nov 1, 1982·The Journal of Investigative Dermatology·R K Winkelmann, J A Carney
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Citations

Jul 1, 1995·Baillière's Clinical Endocrinology and Metabolism·Gilbert J CoteR F Gagel
Jan 7, 2010·The Angle Orthodontist·Brent AccursoCarl M Allen

Related Concepts

Carcinomatosis
Malignant Neoplasm of Mouth
Multiple Endocrine Neoplasia
Thyroid Gland Follicular Adenoma

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