The occurrence of sperm antibodies in human reproduction. I. Comparative new and improved test methods for sperm antibody detection

American Journal of Obstetrics and Gynecology
L MettlerT Gradl

Abstract

The four essential methods for sperm antibody detection are considered and evaluated. The micro-sperm-agglutination and micro-sperm-immobilization tests have been improved and optimized. Quantitative estimation of sperm antibodies was made by an immunoelectrophoresis technique after separation of antibodies from the sera and genital tract secretions by affinity chromatography. Antibodies were typed by line-rocket immunoelectrophoresis. The pathologic errors of the modified tests were found to be small and the biologic errors were tolerable. Satisfactory results were achieved for sperm antibodies belonging to IgA and IgM, but not for other immunoglobulins.

Citations

Aug 1, 1981·American Journal of Reproductive Immunology : AJRI·S B AckermanR J Swanson
Sep 1, 1986·Asia-Oceania Journal of Obstetrics and Gynaecology·S Y ChanW L Tsoi
May 1, 1985·American Journal of Reproductive Immunology and Microbiology : AJRIM·R M IngW R Jones
Jan 1, 1980·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·L MettlerJ Volkmann
Mar 1, 1993·Annals of Saudi Medicine·O Habbal, J McLean

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.