The olfactory adenylyl cyclase type 3 is expressed in male germ cells

FEBS Letters
N DeferJ Hanoune

Abstract

Elements of the olfactory pathway, such as receptors, receptor-desensitization machinery, and cyclic nucleotide-gated channels, are expressed in male germ cells. Here we report the expression, in rat testis, of both adenylyl cyclase type 3 (AC3) and the olfactory G protein subunit, G(alpha)olf. Both are expressed in the same sub-population of germ cells, pachytene spermatocytes to spermatids, and in residual bodies. Neither AC3 nor G(alpha)olf was found in Sertoli or in peritubular cells, as shown by Western blotting and immunocytochemical analyses. It thus appears that male germ cells contain all the elements of the signaling cascade present in olfactory cells.

References

Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·R V Hyne, D L Garbers
Dec 1, 1979·Biology of Reproduction·R V Hyne, D L Garbers
Mar 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·T Braun, R F Dods
Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·G SchlimokG Riethmüller
Aug 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·M S Kang, E Cabib
Jan 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·M K Skinner, I B Fritz
Nov 28, 1980·Biochemical and Biophysical Research Communications·S AdamoV Monesi
Aug 1, 1995·Brain Research. Molecular Brain Research·D HervéM Lévi-Strauss
Oct 13, 1995·The Journal of Biological Chemistry·G A WaymanD R Storm
Jun 1, 1995·Biology of Reproduction·P Leclerc, G S Kopf
Sep 15, 1995·The Journal of Biological Chemistry·G A WaymanD R Storm
Dec 1, 1993·The Journal of Cell Biology·P VanderhaeghenM Parmentier
Jun 1, 1993·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·R Iyengar
Jun 7, 1996·The Journal of Biological Chemistry·R T PremontJ Hanoune
Jul 12, 1996·The Journal of Biological Chemistry·C W Dessauer, A G Gilman
Jan 1, 1996·Annual Review of Pharmacology and Toxicology·R K SunaharaA G Gilman
May 1, 1996·Journal of Neurobiology·D RestrepoD Schild
Apr 4, 1997·Molecular and Cellular Endocrinology·J HanouneN Defer
Jun 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·R KramerA Marquis-Rigault

❮ Previous
Next ❯

Citations

Jan 5, 2000·Molecular Reproduction and Development·R A Harrison, N G Miller
Aug 10, 1999·Developmental Genetics·M Eisenbach
Oct 6, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Johanna FehrIngrid Boekhoff
Apr 2, 1999·Trends in Pharmacological Sciences·W F Simonds
Apr 12, 2006·Nature Reviews. Molecular Cell Biology·Michael Eisenbach, Laura C Giojalas
Jun 9, 1999·Proceedings of the National Academy of Sciences of the United States of America·A M WallaceC C MacDonald
Feb 16, 2005·The Journal of Biological Chemistry·Jason D HoffertMark A Knepper
Jul 28, 2004·The Journal of General Physiology·Michael Eisenbach
Feb 21, 2013·Molecular Human Reproduction·Feng Li
Aug 3, 2013·Molecular Human Reproduction·Claudia Osycka-SalutSilvina Perez-Martinez
Nov 18, 2005·Biology of Reproduction·Sonya M SchuhDonner F Babcock
Mar 27, 2001·Annual Review of Pharmacology and Toxicology·J Hanoune, N Defer
May 5, 2004·Proceedings of the National Academy of Sciences of the United States of America·Kazuhiro KawamuraAaron J W Hsueh
Feb 21, 2004·Proceedings of the National Academy of Sciences of the United States of America·Gloria EspositoByjay S Jaiswal
Sep 6, 2003·Proceedings of the National Academy of Sciences of the United States of America·Bijay S Jaiswal, Marco Conti
Feb 3, 2005·Biological Reviews of the Cambridge Philosophical Society·Stanley Meizel
Mar 26, 2003·Reproduction in Domestic Animals = Zuchthygiene·R A P Harrison
Jul 19, 2006·Cell Motility and the Cytoskeleton·Mamoru Nomura, Victor D Vacquier
Aug 13, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Blythe D Shepard, Jennifer L Pluznick
Jan 29, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jennifer L PluznickMichael J Caplan
Jan 18, 2006·Molecular and Cellular Endocrinology·Marc SpehrHanns Hatt
Feb 5, 2000·Biochimica Et Biophysica Acta·V Iourgenko, L R Levin
Jul 18, 2006·Developmental Biology·Fang XieMarco Conti
Sep 28, 2000·Cell Calcium·N Kraus-Friedmann
Jul 24, 2004·The Journal of Biological Chemistry·Marc SpehrHanns Hatt
Sep 2, 2003·Molecular Reproduction and Development·Rhona W Baxendale, Lynn R Fraser
Feb 28, 2003·Molecular Pharmacology·Hongbing Wang, Daniel R Storm
Jun 26, 2001·The Journal of Biological Chemistry·B S Jaiswal, M Conti
May 15, 2001·American Journal of Physiology. Lung Cellular and Molecular Physiology·K B JourdanN W Morrell
Feb 8, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Karine L RégnauldShahin Emami
Mar 27, 2003·Molecular Reproduction and Development·Rhona W Baxendale, Lynn R Fraser
Sep 1, 2000·American Journal of Physiology. Renal Physiology·N DeferJ Hanoune

❮ Previous
Next ❯

Related Concepts

Related Feeds

Calcium & Bioenergetics

Bioenergetic processes, including cellular respiration and photosynthesis, concern the transformation of energy by cells. Here is the latest research on the role of calcium in bioenergetics.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
J BuckL R Levin
Proceedings of the National Academy of Sciences of the United States of America
B S Jaiswal, M Conti
Proceedings of the National Academy of Sciences of the United States of America
T Braun, R F Dods
© 2022 Meta ULC. All rights reserved