The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again

Cancers
Paul HofmanLaurent Yvan-Charvet

Abstract

It is generally accepted that carcinogenesis and aging are two biological processes, which are known to be associated. Notably, the frequency of certain cancers (including lung cancer), increases significantly with the age of patients and there is now a wealth of data showing that multiple mechanisms leading to malignant transformation and to aging are interconnected, defining the so-called common biology of aging and cancer. OncoAge, a consortium launched in 2015, brings together the multidisciplinary expertise of leading public hospital services and academic laboratories to foster the transfer of scientific knowledge rapidly acquired in the fields of cancer biology and aging into innovative medical practice and silver economy development. This is achieved through the development of shared technical platforms (for research on genome stability, (epi)genetics, biobanking, immunology, metabolism, and artificial intelligence), clinical research projects, clinical trials, and education. OncoAge focuses mainly on two pilot pathologies, which benefit from the expertise of several members, namely lung and head and neck cancers. This review outlines the broad strategic directions and key advances of OncoAge and summarizes some of the i...Continue Reading

References

Jul 19, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A MicheliUNKNOWN EUROPREVAL Working Group
Jan 6, 2006·The Cancer Journal·Rosemary Yancik
Oct 25, 2008·Nature Reviews. Cancer·Christopher C Benz, Christina Yau
Jan 9, 2010·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Angela Grimes, Sathees B C Chandra
Jan 18, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C A BelleraP L Soubeyran
Sep 6, 2012·Critical Reviews in Oncology/hematology·Claire FalandryK Lenhard Rudolph
Jan 8, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C KenisH Wildiers
Jun 12, 2013·Cell·Carlos López-OtínGuido Kroemer
Jul 24, 2013·Trends in Genetics : TIG·Bruno Bernardes de Jesus, Maria A Blasco
Jul 30, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Claire FalandryEric Gilson
Nov 25, 2014·Cell·Brian K KennedyFelipe Sierra
Sep 20, 2015·American Journal of Physiology. Lung Cellular and Molecular Physiology·Jodie BirchJoão F Passos
Jan 1, 2016·Carcinogenesis·Manuel Serrano
Apr 1, 2016·Cancer Discovery·Jerry W Shay
Jun 20, 2016·Journal of Geriatric Oncology·Carole HelisseyStéphane Champiat
Nov 22, 2016·Journal of Thoracic Disease·Esther BarreiroXavier Muñoz
Feb 22, 2017·Biogerontology·Graham Pawelec
Mar 23, 2017·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C A BelleraS Mathoulin-Pélissier
Apr 26, 2017·Trends in Cancer·Andrii I Rozhok, James DeGregori
May 21, 2017·International Review of Cell and Molecular Biology·L Raffaghello, V Longo
Jul 10, 2017·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Amaury DasteAlain Ravaud
Sep 9, 2017·American Journal of Respiratory and Critical Care Medicine·Samuel V KempUNKNOWN TRANSFORM Study Team *
Dec 7, 2017·Current Opinion in Pulmonary Medicine·Abhishek BiswasErik E Folch
Jan 24, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M IliéP Hofman
Jun 3, 2018·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Alexander T FalkMarius Ilié
Jun 6, 2018·Global Health, Epidemiology and Genomics·S A Quaderi, J R Hurst
Jun 14, 2018·Physiological Reviews·Alexandre CaronMathieu Laplante
Jun 16, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C KenisH Wildiers
Jun 29, 2018·Journal of Thoracic Disease·Francesca CasaluceCesare Gridelli
Jul 18, 2018·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Rabia BoulahssassOlivier Guerin
Sep 7, 2018·Nature·Linda PartridgeP Eline Slagboom
Sep 8, 2018·The European Respiratory Journal·Lisa Giovannini-ChamiPascal Barbry
Sep 21, 2018·American Society of Clinical Oncology Educational Book·Ravindran KanesvaranRonald Maggiore
Oct 21, 2018·Environmental Health and Preventive Medicine·Mariko Murata
Nov 9, 2018·Nature Communications·Diego R RevinskiPascal Barbry
Nov 10, 2018·Seminars in Immunology·Barbara BottazziAlberto Mantovani
Nov 26, 2018·Ageing Research Reviews·Alex ZhavoronkovAlex Aliper

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

AVIESAN
OncoAge
HALO AI

Related Concepts

Related Feeds

Cell Aging

This feed focuses on cellular aging with emphasis on mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Cell Aging (Keystone)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Related Papers

The Journal of Thoracic and Cardiovascular Surgery
L Siminovitch
CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
Roger Collier
JAMA : the Journal of the American Medical Association
Tracy Hampton
© 2022 Meta ULC. All rights reserved