PMID: 591809Nov 1, 1977

The onset and establishment of spermatogenesis in rats in relation to gonadotrophin and testosterone levels

The Journal of Endocrinology
F H de Jong, R M Sharpe

Abstract

The concentrations of LH and FSH in the plasma and pituitary gland, and testosterone in the plasma and testes were measured in individual rats between 21 and 180 days of age. Spermatogenesis was quantitated in the same animals and correlations between the various parameters were calculated. The numbers of Sertoli and spermatogenic cells up to pathytene spermatocytes increased in parallel with the peripheral levels of FSH up to days 33 or 35. The concentration of FSH in the plasma started to decrease after day 55, but this decrease could not be correlated with the appearance of any cell type in the testes of the same animals; it was probably due to the high levels of peripheral testosterone at this age. Testicular and plasma levels of testosterone were closely correlated in all age groups studied. The first significant increase occurred between days 39 and 41 and coincided with an increased growth rate of the seminal vesicles and ventral prostate gland. The increase in the concentration of testosterone occurred 10 days after the concentration of LH in the plasma rose to a measurable level. Spermatogenesis had proceeded up to step 16 spermatids at this age.

Citations

Jun 1, 1987·Hormones and Behavior·G T TaylorS Farr
Jun 1, 1982·Physiology & Behavior·G T TaylorD Regan
Aug 1, 1983·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J G LoeberF X van Leeuwen
Jul 30, 1990·Molecular and Cellular Endocrinology·Charles PineauBernard Jégou
Jan 1, 1992·Molecular and Cellular Endocrinology·J P de WinterF H de Jong
Jan 1, 1997·Reproductive Toxicology·W E Berndtson, R H Foote
Apr 1, 1992·Baillière's Clinical Endocrinology and Metabolism·Bernard Jégou
Jul 15, 2011·International Journal of Microbiology·Walter Tarello
Mar 1, 1986·Environmental Health Perspectives·P SjöbergL Plöen
Jan 1, 1986·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J I DelicS M Shalet
Jun 1, 1988·International Journal of Andrology·B P SetchellJ L Zupp
Jun 21, 2005·Molecular and Cellular Endocrinology·A CatizoneM Galdieri
Sep 1, 1982·The American Journal of Anatomy·T Y Wing, A K Christensen
Jan 1, 1984·Archives of Andrology·H EkwallL Plöen
Jan 1, 1983·Journal of Andrology·R M Sharpe, H M Fraser

Related Concepts

Senility
Follicle Stimulating Hormone
Luteozyman
Pituitary Stalk
Prostate
Seminal Vesicles
Spermiogenesis
Testis
Sterotate

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