The ontogeny of the distribution of callosal projection neurons in the rat parietal cortex

The Journal of Comparative Neurology
G O Ivy, H P Killackey

Abstract

The ontogeny of callosal projection neurons in the rat parietal cortex was examined using the retrograde and anterograde transport of horseradish peroxidase (HRP), as well as Golgi and Nissl stains. From postnatal day 0 (PND 0) to early PND 4, the callosal projection neurons are distributed as two continuous horizontal bands of cells which extend throughout the subplate in layers Va and Vc-upper VIa. Neurons within the cortical plate (CP), however, do not transport HRP from a contralateral injection site until PND 3 to early PND 4, when a few cells at the lower CP border are generally labeled. However, by late on PND 4, and more consistently by PND 5, several changes in the distribution of callosal projection neurons take place. First, cells at all levels of the CP become labeled in a sequential fashion, from the lower border upward. Second, gaps, or areas devoid of HRP, become apparent in layer IV of the barrel field area. Third, in the cortical areas containing the gaps, as well as in other areas which are destined not to be callosally connected in the adult, there is a noticeable decrease in the number of cells labeled with HRP. This decrease continues through PND 15 and possibly into adulthood. The foregoing developmental e...Continue Reading

References

Dec 1, 1976·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M M Mesulam
Sep 15, 1977·The Journal of Comparative Neurology·S P Wise, E G Jones
May 5, 1979·Brain Research·R D Lund, D E Mitchell
Mar 15, 1978·The Journal of Comparative Neurology·S P Wise, E G Jones
Apr 7, 1978·Brain Research·R D LundG H Henry
Jun 15, 1978·The Journal of Comparative Neurology·G M Shoukimas, J W Hinds
Oct 1, 1978·The Journal of Comparative Neurology·R M Akers, H P Killackey
Jan 15, 1979·The Journal of Comparative Neurology·H P Killackey, G R Belford
Feb 15, 1977·The Journal of Comparative Neurology·F L Rice, H Van der Loos
May 1, 1967·Experimental Neurology·A Globus, A B Scheibel
Jul 5, 1974·Brain Research·S Jacobson, J Q Trojanowski
Mar 1, 1968·The Anatomical Record·S P Hicks, C J D'Amato
Apr 1, 1977·Neuroscience Letters·G M InnocentiR Caminiti
Jun 1, 1946·The Journal of Comparative Neurology·W J S KRIEG

❮ Previous
Next ❯

Citations

Sep 26, 1997·The Journal of Comparative Neurology·E M BrennanM E Blue
Sep 26, 1997·The Journal of Comparative Neurology·L C deAzevedoR Lent
Aug 12, 1999·Annals of Neurology·A R JennerA M Galaburda
Mar 1, 1989·Metabolic Brain Disease·N ZecevićL Rakic
Jul 1, 1992·Neuroscience and Behavioral Physiology·Z N BakhchievaN O Movsesyan
Jun 9, 2007·Journal of Neural Transmission·A V WitteG Teuchert-Noodt
Aug 1, 1993·Journal of Neuroscience Methods·J P Ternaux, P Portalier
Aug 1, 1981·Brain Research·G O Ivy, H P Killackey
May 1, 1984·Brain Research·R D LundP W Land
Jul 1, 1984·Brain Research·D Wahlsten
Sep 1, 1985·Brain Research·M K Floeter, E G Jones
Jan 1, 1985·Brain Research·R W RhoadesS E Fish
Nov 1, 1990·Brain Research. Developmental Brain Research·J R BuchhalterM A Dichter
Jun 21, 1991·Brain Research. Developmental Brain Research·P R Huttenlocher, C Bonnier
Nov 21, 1995·Brain Research. Developmental Brain Research·C P LiB E Greger
Oct 1, 1989·Trends in Neurosciences·D D O'Leary
Aug 1, 1988·Neuroscience Research·B R PayneP Cornwell
Nov 1, 1992·Progress in Neurobiology·G D RosenA M Galaburda
Jul 1, 1992·Progress in Neurobiology·I FerrerC Auladell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.