The ontogeny of the somatotropic axis in Hereford calves from birth to one year of age and its response to administration of exogenous bovine somatotropin

Journal of Animal Science
Kristen E GovoniSteven A Zinn

Abstract

Administration of exogenous bovine ST (bST) increases growth rate, feed efficiency, and carcass quality in beef cattle. The magnitude of response to bST in beef cattle is variable and related to the age of the animal. Our objective was to determine the response of the somatotropic axis, in particular IGF-I, IGFBP-2, and IGFBP-3, to bST treatment from birth to 1 yr of age. Blood samples were collected before and after a single injection of bST (500 mg) every 50 d from birth to 1 yr of age in male and female Hereford calves. Body weights and serum concentrations of ST, IGF-I, IGFBP-2, and IGFBP-3 were determined. At birth, serum concentrations of ST, IGF-I, and IGFBP-3 increased (P < 0.05) following bST treatment. From 50 to 350 d of age, average concentrations of ST and IGF-I were greater (P < 0.05) in males, whereas IGFBP-2 concentrations were greater (P < 0.05) in females. No gender differences in IGFBP-3 concentrations were observed. Following bST treatment, IGF-I increased (P < 0.05) from 50 to 350 d of age, IGFBP-2 decreased (P < 0.05) from 50 to 200 d of age, and IGFBP-3 increased (P < 0.05) at 250 d of age. At 250 d of age, baseline concentrations of IGFBP-2 decreased (P < 0.05). Due to the positive response of IGFBP-3 an...Continue Reading

References

Feb 1, 1992·Journal of Animal Science·W M MoseleyW H Claflin
Aug 1, 1992·The Journal of Nutrition·K L HouseknechtD F Smith
Jul 1, 1989·Acta Endocrinologica·H Ronge, J W Blum
Apr 1, 1995·Journal of Animal Science·R L PrestonC A Baile
May 15, 1998·Journal of Animal Science·M W TrippS A Zinn
Nov 24, 1999·Journal of Animal Science·R J HarrellD E Bauman
Apr 4, 2001·The Journal of Nutrition·H C FreakeS A Zinn
Apr 23, 2002·Biology of Reproduction·Kristen E GovoniSteven A Zinn

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Citations

Jan 20, 2010·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Julie P RichmondSteven A Zinn
Jul 12, 2011·Cellular Reprogramming·JungEun ParkByeongChun Lee
Nov 19, 2018·Translational Animal Science·Philipe MorielJose L M Vasconcelos
Jul 12, 2016·Veterinary World·Nasr-Eldin M ArefHammad Zaghloul Hammad
Apr 16, 2013·Journal of Agricultural and Food Chemistry·Susann Katrina Julie LudwigMichel Wilhelmus Franciscus Nielen

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