Abstract
Complex fractionated atrial electrogram (CFAE)-targeted catheter ablation (CFAE ablation) requires a high rate of atrial fibrillation (AF) termination to provide good outcomes. We determined the optimal settings of CFAE software. In our 430 consecutive patients, AF was terminated in 97 (234/242) and 79% (149/188) of patients with paroxysmal and persistent AF, respectively, by CFAE ablation combined with (31%) or without (69%) pulmonary vein isolation, occasionally with nifekalant infusion. We analyzed 109 consecutive patients who underwent CFAE ablation to determine the optimal settings for comparing subjective versus objective decisions by the CFAE software on CARTO3. We compared three settings: the default setting (0.05-0.15 mV, 50-120 ms) and two modified settings (#1: 0.05-0.30 mV, 40-70 ms, #2: 0.05-0.13 mV, 10-20 ms). We retrospectively analyzed 11,425 points during left atrial mapping before ablation and 10,306 points that were subjectively detected and ablated as CFAE points. An interval confidence level ≥6 denoted a site with CFAE. With the default setting, the accuracy, sensitivity, specificity, positive productive value, and negative productive values were 67, 42, 77, 48, and 73%, respectively. With modified setting ...Continue Reading
References
Sep 3, 1998·The New England Journal of Medicine·M HaïssaguerreJ Clémenty
Nov 21, 2001·Circulation·C PapponeO Alfieri
Jan 31, 2002·Pacing and Clinical Electrophysiology : PACE·L KanagaratnamA Natale
Mar 6, 2002·Circulation·Hakan OralFred Morady
Jul 24, 2003·Journal of the American College of Cardiology·Carlo PapponeOttavio Alfieri
Aug 6, 2003·Circulation·Giuseppe StabileAntonio De Simone
Jun 3, 2004·Journal of the American College of Cardiology·Koonlawee NademaneeTachapong Ngarmukos
Feb 23, 2005·Circulation·Riccardo CappatoAllan Skanes
Jun 2, 2005·JAMA : the Journal of the American Medical Association·Oussama M WazniAndrea Natale
Oct 11, 2005·European Heart Journal·Giuseppe StabileDino Franco Vitale
Nov 24, 2005·Journal of Cardiovascular Electrophysiology·Michel HaïssaguerrePierre Jaïs
Apr 12, 2006·Circulation·Hakan OralFred Morady
Jun 20, 2006·European Heart Journal·Stephan WillemsThomas Meinertz
May 16, 2007·Circulation·Hakan OralFred Morady
Jun 9, 2007·Heart Rhythm : the Official Journal of the Heart Rhythm Society·UNKNOWN European Heart Rhythm Association (EHRA)Richard J Shemin
Feb 26, 2008·Journal of the American College of Cardiology·Koonlawee NademaneeTachapong Ngarmukos
Sep 2, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Heidi Luise EstnerIsabel Deisenhofer
Feb 12, 2009·Journal of Cardiovascular Electrophysiology·Isabel DeisenhoferGabriele Hessling
Feb 4, 2010·Journal of cardiology·Koonlawee NademaneeBrett Gidney
Mar 31, 2010·Journal of cardiology·Michiharu SengaMasaaki Ito
Aug 25, 2011·Journal of cardiology·Yasuhisa IrikiChuwa Tei
Feb 9, 2012·Journal of Cardiovascular Electrophysiology·Hitoshi IchikiChuwa Tei
Apr 25, 2012·Journal of cardiology·Ryuichi MaenosonoTeruto Hashiguchi
Aug 21, 2013·Pacing and Clinical Electrophysiology : PACE·Hitoshi IchikiChuwa Tei
Citations
May 2, 2016·Journal of cardiology·Akino YoshimuraMitsuru Ohishi
May 30, 2019·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Fuminori NaminoIkuro Maruyama
Nov 22, 2018·Frontiers in Physiology·Ghassen ChenitiFrederic Sacher
Apr 23, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Issei YoshimotoMitsuru Ohishi
Apr 30, 2021·Journal of Medical Ultrasonics·Ryuichi MaenosonoTeruto Hashiguchi