PMID: 8595655Dec 1, 1995Paper

The orientation of gene maps by recombination of flanking markers for the am locus of Neurospora crassa

Current Genetics
F J Bowring, David Catcheside

Abstract

Fincham (1967), Smyth (1973 b) and Rambosek and Kinsey (1983) have each generated fine-structure maps of the am gene of Neurospora crassa. Each map had a consistent linear order of alleles but the assignment of an orientation with respect to other linkage group-V loci differed. Fincham found the end marked by the am6 allele to be at the distal end of the locus, Smyth found am6 to be at the proximal end while the data of Rambosek and Kinsey did not suggest an orientation. Smyth s orientation has been adopted as the standard, but not unreservedly. We have aligned the genetic and physical maps of the am gene, showing that am6 is at the distal end, supporting Fincham's orientation. However, we suggest that an assumption used to orient fine structure genetic maps is flawed and that the conflicting orientation between these three studies follows from the different choice of flanking markers.

References

Oct 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M E CaseN H Giles
Jan 1, 1990·Annual Review of Genetics·E U Selker
Apr 1, 1973·Australian Journal of Biological Sciences·D R Smyth
Oct 1, 1974·Australian Journal of Biological Sciences·D E Catcheside
Jul 3, 1969·Molecular & General Genetics : MGG·H G Kolmark
Jun 1, 1971·Canadian Journal of Genetics and Cytology. Journal Canadien De Génétique Et De Cytologie·P Haysman, H B Howe
Feb 1, 1970·Journal of Clinical Pathology·D H Smyth
Jul 1, 1969·Mutation Research·H G Kolmark
Jun 1, 1967·Genetics·H F Terenzi, J L Reissig
May 1, 1952·Proceedings of the National Academy of Sciences of the United States of America·M B Mitchell, H K Mitchell
Jul 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·S J Vollmer, C Yanofsky
Oct 1, 1983·Genetics·J A Rambosek, J A Kinsey

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Citations

Mar 29, 2001·Fungal Genetics and Biology : FG & B·D D Perkins, R H Davis

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