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The origin of MHC class II gene polymorphism within the genus Mus

Nature

Apr 14, 1988

T J McConnellEdward K Wakeland

Abstract

The I region of the major histocompatibility complex (MHC) of the mouse (H-2) contains a tightly-linked cluster of highly polymorphic genes (class II MHC genes) which control immune responsiveness. Speculation on the origin of this polymorphism, which is believed to be essential for the...read more

Mentioned in this Paper

Short Interspersed Nucleotide Elements
Immune Response
Muridae
Exons
Restriction Fragment Length Polymorphism
Restriction Site
Genes, MHC Class II
Major Histocompatibility Complex
Homologous Sequences, Nucleic Acid
Nucleotides
Paper Details
References
  • References13
  • Citations57
12
  • References13
  • Citations57
12345...

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The origin of MHC class II gene polymorphism within the genus Mus

Nature

Apr 14, 1988

T J McConnellEdward K Wakeland

PMID: 2895893

DOI: 10.1038/332651a0

Abstract

The I region of the major histocompatibility complex (MHC) of the mouse (H-2) contains a tightly-linked cluster of highly polymorphic genes (class II MHC genes) which control immune responsiveness. Speculation on the origin of this polymorphism, which is believed to be essential for the...read more

Mentioned in this Paper

Short Interspersed Nucleotide Elements
Immune Response
Muridae
Exons
Restriction Fragment Length Polymorphism
Restriction Site
Genes, MHC Class II
Major Histocompatibility Complex
Homologous Sequences, Nucleic Acid
Nucleotides

Similar Papers Found In These Feeds

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Nature | Cell | Science

Discover the latest research from the prestigious journals: Nature, Cell, and Science.

Related Papers

Nature

MHC polymorphism pre-dating speciation

NatureSeptember 15, 1988
F FigueroaJ Klein
Paper Details
References
  • References13
  • Citations57
12
  • References13
  • Citations57
12345...
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