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The origin of polynucleotide-directed protein synthesis

Journal of Molecular Evolution

Dec 1, 1989

Leslie E Orgel

PMID: 2482368

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Abstract

If protein synthesis evolved in an RNA world it was probably preceded by simpler processes by means of which interaction with amino acids conferred selective advantage on replicating RNA molecules. It is suggested that, at first, the simple attachment of amino acids to the 2'(3')-termin...read more

Mentioned in this Paper

Protein Biosynthesis
Polynucleotides
Transcription Initiation
RNA
Antifibrinolytic amino acids
Biological Evolution
Phosphaden
Aminoacylation
Amino Acids, I.V. solution additive
Paper Details
References
  • References32
  • Citations40
1234

The origin of polynucleotide-directed protein synthesis

Journal of Molecular Evolution

Dec 1, 1989

Leslie E Orgel

PMID: 2482368

DOI:

Abstract

If protein synthesis evolved in an RNA world it was probably preceded by simpler processes by means of which interaction with amino acids conferred selective advantage on replicating RNA molecules. It is suggested that, at first, the simple attachment of amino acids to the 2'(3')-termin...read more

Mentioned in this Paper

Protein Biosynthesis
Polynucleotides
Transcription Initiation
RNA
Antifibrinolytic amino acids

Related Papers

Paper Details
References
  • References32
  • Citations40
1234

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