The origin of the spinal subdural space: ultrastructure findings

Anesthesia and Analgesia
Miguel Angel ReinaAgustín Fernández

Abstract

Previous studies of samples from cranial meninges have created doubts about the existence of a virtual subdural space. We examined the ultrastructure of spinal meninges from three human cadavers immediately after death to see whether there is a virtual subdural space at this level. The arachnoid mater had two portions: a compact laminar portion covering the dural sac internal surface and a trabecular portion extending like a spider web around the pia mater. There was a cellular interface between the laminar arachnoid and the internal layer of the dura that we called the dura-arachnoid interface. There was no subdural space in those specimens where the dura mater was macroscopically in continuity with the arachnoid trabecules. In the specimens where the dura mater was separated from the arachnoid, we found fissures in between the neurothelial cells that extended throughout the interface. We hypothesize that the subdural space would have its origin within the dura-arachnoid interface when the neurothelial cells break up, creating in this way a real subdural space. The subdural space was not seen under transmission electron microscopy in samples of human spinal meninges where surgical manipulation was avoided. Scanning electron mi...Continue Reading

References

Nov 15, 1975·The Journal of Comparative Neurology·S NabeshimaM W Brightman
May 1, 1991·The Anatomical Record·D E Haines
May 1, 1991·The Anatomical Record·R G Frederickson
Jan 1, 1988·Neuropathology and Applied Neurobiology·R AlcoladoD Garrod
Jul 1, 1967·Journal of Neuropathology and Experimental Neurology·J D Waggener, J Beggs
Feb 1, 1996·Anaesthesia·C J Ralph, M P Williams

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Citations

Jan 6, 2010·Regional Anesthesia and Pain Medicine·Nir Hoftman, F Michael Ferrante
Oct 13, 2011·Regional Anesthesia and Pain Medicine·Miguel Angel ReinaJosé Antonio De Andrés
Sep 12, 2014·F1000Research·Beatriz Nistal-Nuño, Manuel Ángel Gómez-Ríos
Dec 10, 2016·Journal of Biomechanical Engineering·Yi HuaLinxia Gu
May 16, 2019·Journal of Korean Neurosurgical Society·Hasan Emre AydınAli Arslantas
Apr 24, 2004·Anesthesia and Analgesia·Miguel Angel ReinaJosé Antonio De Andrés
Jan 25, 2007·Neurologia Medico-chirurgica·Myoung Soo KimJong Joo Rhee
Nov 11, 2009·Regional Anesthesia and Pain Medicine·Clive Collier
Jun 1, 2016·Operative Neurosurgery·Laurent SakkaGuillaume Coll
Feb 1, 2020·Medicine·Caroline Turbelin, Jihad Mallat
Apr 23, 2020·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·John C Drummond, Roland R Lee
May 29, 2004·Anesthesiology·Pamela J AngleSusan Cromwell
Oct 5, 2006·Current Opinion in Anaesthesiology·Andrea Casati, Federico Vinciguerra
Oct 12, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Adam L SandlerRick Abbott
Dec 15, 2006·Pain Practice : the Official Journal of World Institute of Pain·Rinoo V Shah, James E Heavner
May 11, 2007·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Marek MoskalaAdam J Miodonski
Dec 10, 2016·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Euddeum ShimHeung Sik Kang
Aug 22, 2017·Anesthesiology and Pain Medicine·Omar ViswanathMichael Baskin
Apr 25, 2012·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Milo StanisicTerje Sæhle
Oct 14, 2011·Neuromodulation : Journal of the International Neuromodulation Society·Jason E Pope, Michael Stanton-Hicks
May 14, 2009·Regional Anesthesia and Pain Medicine·Yushi U Adachi, Shigehito Sato
Dec 15, 2011·Anaesthesia and Intensive Care·C B CollierF Machés
Feb 4, 2014·Case Reports in Anesthesiology·Kesavan SadacharamMichael S Green
Apr 9, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Elmar M DelhaasAad van der Lugt
Apr 15, 2011·Korean journal of anesthesiology·Joo Sun YunYoun-Woo Lee
Jan 17, 2021·Emergency Radiology·Riku M VierunenFrank V Bensch
Jun 10, 2005·Morphologie : Bulletin De L'Association Des Anatomistes·L Sakka, J Chazal
Feb 27, 2017·Journal of Clinical Anesthesia·Bradley H Lee, Matthias Braehler

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