The origin of the spinomesencephalic tract in the rat: an anatomical study using the retrograde transport of horseradish peroxidase

The Journal of Comparative Neurology
D. MenétreyJ M Besson

Abstract

An anatomical technique based on the retrograde transport of horseradish peroxidase (HRP) was used to investigate the projections of spinal cord neurons to the mesencephalic tegmentum in the rat. Restricted unilateral injections were confined to central grey, cuneiformis areas, and superior colliculus. Injections into all these loci produced labeling in similar spinal areas. Only quantitative differences were noted. In the spinal grey matter, numerous labeled cells were regularly encountered in the marginal zone, the lateral part of the neck of the dorsal horn, and the dorsal grey commissure. Projections from the marginal zone and neck of the dorsal horn were predominantly contralateral. In the white matter, a pronounced bilateral labeling was observed in the nucleus of the dorsolateral funiculus, thus confirming our previous electrophysiological findings (Menétrey et al., '80). This distribution of labeled cells was commonly observed throughout the whole length of the cord. Additional sites of projecting cells have also been identified at the most rostral levels (obex, C1, C2). They mostly derived from spinal extensions of the dorsal column nuclei and lateral cervical nucleus contralaterally; from the lateral ventral horns bil...Continue Reading

References

Feb 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M M Mesulam
Oct 15, 1976·The Journal of Comparative Neurology·C B SaperW M Cowan
Dec 1, 1976·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M M Mesulam
Mar 1, 1979·The Journal of Comparative Neurology·G J GieslerA I Basbaum
Dec 1, 1978·Science·W D WillisD R Kenshalo
Dec 15, 1978·The Journal of Comparative Neurology·C B SaperW M Cowan
Jul 15, 1979·The Journal of Comparative Neurology·Alan R Light, E R Perl
Dec 15, 1979·The Journal of Comparative Neurology·W D WillisR B Leonard
May 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·R SimantovS H Snyder
Jul 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·T HökfeltG Nilsson
Nov 1, 1978·The Journal of Comparative Neurology·M SarP Cuatrecasas
Mar 15, 1979·The Journal of Comparative Neurology·R P BarberS E Leeman
Mar 9, 1979·Experimental Brain Research·F CerveroV Molony
Jul 1, 1979·The Journal of Comparative Neurology·G J GieslerJ C Liebeskind
Sep 8, 1978·JAMA : the Journal of the American Medical Association·H E NinoS Martin
Sep 22, 1978·Brain Research·K J Berkley, P J Hand
Aug 15, 1978·Experimental Brain Research·D A Hopkins, G Holstege
Sep 1, 1978·Experimental Neurology·J Yamada, K Otani
Feb 15, 1979·The Journal of Comparative Neurology·M S KriegerD W Pfaff
Mar 15, 1979·The Journal of Comparative Neurology·S B EdwardsB E Stein
May 15, 1976·The Journal of Comparative Neurology·L W Swanson
Jan 1, 1977·The Journal of Comparative Neurology·P J Hand, T Van Winkle
Dec 17, 1976·Brain Research·G J GieslerJ M Besson
Oct 15, 1975·The Journal of Comparative Neurology·C M Antonetty, K E Webster
Aug 1, 1966·The Journal of Comparative Neurology·H Ha, C N Liu
Sep 1, 1968·Brain Research·D G Gwyn, H A Waldron
Jul 1, 1973·Journal of Neurophysiology·D L TrevinoW D Willis
Mar 1, 1974·Journal of Neurophysiology·W D WillisR A Maunz
Jan 18, 1974·Brain Research·D Albe-FessardY Lamour
May 17, 1973·Brain Research·P M GrovesG V Rebec
Jan 1, 1974·International Journal of Health Services : Planning, Administration, Evaluation·C Muller
Jan 1, 1969·Journal of Neurosurgery·B S NasholdD G Slaughter
May 1, 1969·The Journal of Comparative Neurology·M Matsushita
Apr 1, 1970·The Journal of Comparative Neurology·M Matsushita
Mar 1, 1970·Journal of Neurophysiology·B N Christensen, E R Perl
May 1, 1970·The Journal of Comparative Neurology·R C TruexP L Gildenberg
Oct 28, 1970·Brain Research·J M LiebmanJ C Liebeskind
Jul 1, 1971·The Journal of Comparative Neurology·D M Schroeder, J A Jane
Aug 1, 1967·The Journal of Comparative Neurology·R D Lund, K E Webster
Apr 1, 1980·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·V S Seybold, R Elde
Aug 1, 1980·The Journal of Comparative Neurology·S G Feldman, L Kruger
Mar 15, 1980·The Journal of Comparative Neurology·R M BecksteadR Norgren
Jan 10, 1981·The Journal of Comparative Neurology·G J GieslerW D Willis
Aug 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J I MorrellD W Pfaff
Sep 10, 1981·The Journal of Comparative Neurology·H P Killackey, R S Erzurumlu
Jan 1, 1954·Journal of Neuropathology and Experimental Neurology·E A SPIEGELE G SZEKELY
Nov 1, 1955·The American Journal of Physiology·F MORIN
Jul 1, 1958·Journal of Neurophysiology·R MELZACKW K LIVINGSTON
Dec 30, 1960·Acta Physiologica Scandinavica·G M KOLMODIN, C R SKOGLUND
Apr 1, 1959·The Journal of Comparative Neurology·F D ANDERSON, C M BERRY
Nov 1, 1962·The American Journal of Physiology·M E OLDS, J OLDS
Dec 8, 1978·Brain Research·B E Stein, J P Dixon

Citations

Aug 1, 1987·Naunyn-Schmiedeberg's Archives of Pharmacology·B J Morris, A Herz
Jan 1, 1984·Anatomy and Embryology·M Björkeland, J Boivie
Mar 1, 1993·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·M Sosnowski
Jul 26, 1991·Brain Research·M V Smith, A V Apkarian
May 21, 1993·Brain Research. Developmental Brain Research·T Seki, Y Arai
Jun 1, 1994·Trends in Neurosciences·G J GieslerR J Dado
Aug 1, 1995·Progress in Neurobiology·M M Behbehani
Sep 7, 1984·Neuroscience Letters·J. De PommeryD. Menétrey
Jul 31, 1985·Neuroscience Letters·D. MenétreyF Roudier
Jan 2, 1987·Neuroscience Letters·D. MenétreyJ. De Pommery
Feb 17, 1995·Neuroscience Letters·S Günther, R Necker
Mar 26, 2013·Journal of Chemical Neuroanatomy·Dusica Bajic, Herbert K Proudfit
Aug 23, 2003·Brain Research·Monica Levy Andersen, Sergio Tufik
Jan 22, 2002·Neuroscience and Biobehavioral Reviews·K A Keay, R Bandler
Feb 12, 1999·Brain Research. Brain Research Reviews·G W Lu, W D Willis
Jun 25, 1998·Behavioural Brain Research·V G Van der Horst, G Holstege
Oct 1, 1992·The European Journal of Neuroscience·D. MenétreyM. Thomasset
Jul 1, 1993·The European Journal of Neuroscience·M Antal, Erika Polgár
Jun 26, 2008·The International Journal of Neuroscience·Stephanie Reyes, John Mitrofanis
May 17, 2002·The Journal of Physiology·Ruth Ruscheweyh, Jürgen Sandkühler
Jul 20, 2002·Brain Research Bulletin·Terence V Sewards, Mark Sewards
Aug 23, 2008·The Journal of Comparative Neurology·Khulood M Al-KhaterAndrew J Todd
Mar 11, 2009·The Journal of Comparative Neurology·João M BrazA I Basbaum
Apr 1, 2004·Brain Research·Tatiana F AlmeidaSergio Tufik
Sep 20, 1988·Brain Research·K D ClifferG J Giesler
Jan 14, 2017·The European Journal of Neuroscience·Griselda M YvonePatricia E Phelps
Nov 19, 2003·The European Journal of Neuroscience·R C SpikeAndrew J Todd
Dec 4, 2003·The Journal of Comparative Neurology·Caroline Gauriau, Jean-François Bernard
Mar 17, 2004·The Journal of Comparative Neurology·L J MoutonG Holstege
Jul 13, 2002·The Journal of Comparative Neurology·Patrick D WallMatt S Ramer
Jun 29, 2004·The Journal of Comparative Neurology·Tracy S TranPatricia E Phelps
Feb 8, 1988·The Journal of Comparative Neurology·G J GieslerG Grant
May 19, 1997·The Journal of Comparative Neurology·V S SeyboldB R Southwell
Nov 1, 1983·The Journal of Comparative Neurology·R L NahinG J Giesler
Jun 25, 2005·The Journal of Comparative Neurology·Sarah E SlackSophie Pezet
Jan 1, 1986·Somatosensory Research·J L HyldenG J Bennett
Feb 19, 1985·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·W D Willis
Apr 20, 1983·The Journal of Comparative Neurology·G A Kevetter, W D Willis
Dec 16, 1996·The Journal of Comparative Neurology·V G VanderhorstG Holstege
Oct 1, 1992·The European Journal of Neuroscience·D. MenétreyK. G. Baimbridge
Jun 4, 2020·The European Journal of Neuroscience·Griselda M YvonePatricia E Phelps
Apr 12, 2000·Journal of Neurophysiology·H BesterJ F Bernard
Dec 22, 2020·The Journal of Physiology·Kazuhiro HoriiYasutake Shimizu

Related Concepts

Afferent Pathways
Functional Cerebral Localization
August Rats
Esthesia
Spinal Cord
Cerebral Peduncle

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.