The OSA-5: Development and validation of a brief questionnaire screening tool for obstructive sleep apnea in children

International Journal of Pediatric Otorhinolaryngology
Han Jie SohGillian M Nixon

Abstract

To develop and test a screening tool based on the OSA-18 questionnaire for triage of referrals for sleep-disordered breathing (SDB) in children. Consecutive children aged >2y without major comorbidities referred for polysomnography (PSG) or overnight oximetry for suspected obstructive sleep apnea (OSA) between 11 January and 31 May 2017 were included. OSA was defined by an obstructive apnea/hypopnea index (OAHI) >1event/h on PSG or an abnormal overnight oximetry (McGill Oximetry Score 2-4). An 11-item questionnaire derived from a previous validation study of the OSA-18 underwent exploratory factor analysis (EFA) with varimax rotation. ANOVA identified questions associated with the presence of OSA. This informed a 5-question, 4-category instrument, scored 0-15 (the OSA-5), that was tested prospectively on 112 children having PSG. 420 children (2.0-17.9y, 43% female) met the inclusion criteria, including 366 complete questionnaires. EFA resulted in a 3-factor structure. ANOVA identified 5 questions from one factor that were independently associated with a diagnosis of OSA: snoring, breath holding, choking, mouth breathing and parental concern. Mean OSA-5 scores with and without OSA were 7.7 vs 4.5 (p < 0.001). Thirty-four percent...Continue Reading

Citations

Nov 23, 2019·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Haytham KubbaRachel Harwood
May 12, 2020·Frontiers in Psychiatry·Tabitha Sen, Karen Spruyt
Feb 4, 2021·International Journal of Pediatric Otorhinolaryngology·Albane B R MaggioRegula Corbelli
Feb 6, 2021·International Archives of Otorhinolaryngology·Juliana Alves Sousa CaixetaMelissa Ameloti Gomes Avelino

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