The outcome of surgical treatment for elderly patients with gastric carcinoma

Journal of Surgical Oncology
Katsunobu SakuraiKosei Hirakawa

Abstract

The aim of this study was to clarify the operative mortality and long-term survival of gastrectomy for elderly patients with gastric cancer. A total of 461 patients who underwent gastrectomy for gastric cancer in our hospital were classified as elderly group (≥80 years-old, 95 patients) and control group (60-69 years-old, 366 patients). The frequency of comorbidities was significantly (P < 0.05) higher in elderly group (74.7%) than that in the control group (49.5%). No significant difference of the postoperative complication rate was found between the elderly group (23.2%) and the control group (23.2%). Adjuvant chemotherapy was 9.5% in the elderly group, which was significantly less than 29.0% of the control group (P < 0.05). Stage II and III elderly patients had worse disease specific survival (DSS) than controls did. In the elderly, overall survival (OS) was significantly worse than DSS in stage I patients (P < 0.05). The operative complication rate of elderly patients was comparable to the control group. Comorbidity and occurrence of secondary malignant disease should be followed for elderly patients at stage I. For stage II and III disease patients, a novel drug which is acceptable for the elderly is needed as a postoperat...Continue Reading

References

Jul 1, 1995·Journal of the American Geriatrics Society·D R Thomas, C S Ritchie
Apr 17, 1998·Japanese Journal of Clinical Oncology·H KataiK Maruyama
Jun 10, 2000·Journal of Gastroenterology and Hepatology·Y OtaniM Kitajima
Apr 20, 2004·The Journal of Surgical Research·Reza F SaidiPaul S Dudrick
Aug 3, 2004·The British Journal of Surgery·K YasudaS Kitano
Dec 24, 2004·Surgical Oncology·Hitoshi KataiTakeo Fukagawa
Aug 27, 2005·Journal of Surgical Oncology·Eigo OtsujiHisakazu Yamagishi
Nov 29, 2005·World Journal of Surgery·Erito MochikiHiroyuki Kuwano
Jul 20, 2006·World Journal of Surgery·Stephen GretschelPeter M Schlag
Nov 6, 2007·The New England Journal of Medicine·Shinichi SakuramotoUNKNOWN ACTS-GC Group
Jul 4, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Masanori TokunagaToshiharu Yamaguchi
Aug 19, 2008·Japanese Journal of Clinical Oncology·Tomohiro MatsudaUNKNOWN Japan Cancer Surveillance Research Group
Feb 21, 2009·Journal of the American College of Surgeons·Sun-Hwi HwangKuhn Uk Lee
Jun 23, 2009·The Journal of Surgical Research·Hiroyuki YamadaKenichi Sugihara
Jul 30, 2009·Annals of Surgery·Pierre A ClavienMasatoshi Makuuchi
Feb 22, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Shunji EndoWataru Kamiike
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
May 17, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Takeshi Sano, Takashi Aiko
Jul 1, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Toru AoyamaAkira Tsuburaya
Jun 26, 2012·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Atsushi NashimotoMichio Kaminishi
Apr 23, 2013·International Journal of Surgery·Hiroyuki YamadaKiyofumi Yamagishi
Sep 12, 2013·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Yasuhiro KoderaMichitaka Fujiwara
Oct 2, 2013·World Journal of Surgery·Hiroki TakeshitaEigo Otsuji

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Citations

Dec 30, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C-J ZhouZ Yu
Aug 5, 2016·Annals of Surgical Oncology·Jun-Young YangHan-Kwang Yang
Oct 21, 2016·International Journal of Surgery·Leonardo SolainiGuido Alberto Massimo Tiberio
Mar 7, 2018·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Sung Ryol LeeChang Hak Yoo
Apr 24, 2018·The British Journal of Surgery·S D NelenUNKNOWN Dutch Upper Gastrointestinal Cancer Audit group
Feb 7, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Natalie LiuAnne O Lidor
Dec 13, 2017·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Trevor D HamiltonJulie Hallet
May 31, 2020·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Fei ShanJia-Fu Ji
May 12, 2017·Updates in Surgery·Francesco CasellaRoberto Verzaro
Jun 28, 2019·Journal of Gastric Cancer·Maciej CiesielskiJacek Zieliński

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Methods Mentioned

BETA
dissection
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Software Mentioned

JMP

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